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腹腔镜下食管动力差或食管旁疝患者的食管裂孔疝修补术。

Laparoscopic hiatal hernia repair in patients with poor esophageal motility or paraesophageal herniation.

作者信息

Livingston C D, Jones H L, Askew R E, Victor B E, Askew R E

机构信息

Austin Surgeons, PLLC, Texas 78756, USA.

出版信息

Am Surg. 2001 Oct;67(10):987-91.

Abstract

Laparoscopic repair for gastroesophageal reflux disease is now an accepted therapy. However, controversy exists with regard to the choice of operation between complete 360-degree Nissen fundoplication versus partial 270-degree Toupe fundoplication. In addition there is some controversy with regard to the proper choice of operation in patients with poor esophageal motility. Another class of hiatal hernia patients are those patients with paraesophageal herniation. Questions regarding the approach to these patients include whether or not to use a reflux procedure at the time of repair and the role of mesh in repair of these large hernias. This retrospective study was undertaken to compare the results of laparoscopic Nissen fundoplication and Toupe fundoplication in patients with both normal and abnormal esophageal motility. In addition the subset of patients with paraesophageal herniation was studied in an effort to ascertain the best surgical approach in these patients. In this study a retrospective analysis was performed on 188 consecutive patients during the period 1995 to 2001. All patients who presented with hiatal hernia surgical problems during this period were included. Endoscopy was performed in all patients with esophageal reflux. Manometry was performed in all patients except those presenting as emergency incarcerations. pH probe testing was performed in those patients in whom it was deemed necessary to establish the diagnosis. Upper gastrointestinal radiographs were used to define anatomy in paraesophageal hernia patients when possible. All patients with esophageal reflux were first treated with a trial of medical therapy. Patients with esophageal reflux and normal esophageal motility underwent 360-degree Nissen fundoplication. Those patients with poor esophageal motility (less than 65 mm of mercury) underwent laparoscopic 270-degree Toupe fundoplication. Patients presenting with paraesophageal herniation underwent laparoscopic repair. When possible esophageal manometry was performed on these patients preoperatively and if normal peristalsis was documented a Nissen fundoplication was performed. If poor esophageal motility was documented before surgery a Toupe fundoplication was performed. Mesh reinforcement of the diaphragmatic hiatus was used if necessary to complete a repair without tension. Patients were followed both by their primary gastroenterologist and their surgeon. Follow-up studies including endoscopy, pH probe, and upper gastrointestinal series were used as necessary in the postoperative period to document any problems as they occurred. Of the 188 patients in the study 141 patients underwent Nissen fundoplication, 21 patients underwent Nissen fundoplication and repair of paraesophageal hernia, 15 underwent Toupe fundoplication, seven underwent Toupe and paraesophageal hernia repair, and four paraesophageal hernia repair alone. One hundred eighty-three patients underwent a laparoscopic operation. Five patients of the 188 underwent an initial open operation-two of these patients because of the size of their paraesophageal hernia. Three of these patients had reoperations of remote operations done years before at other institutions. Twenty-two patients with poor esophageal motility (11.7 %) were included in the study. Fifteen patients required Toupe fundoplication whereas seven patients required Toupe fundoplication and repair of paraesophageal hernias. Mesh repair of paraesophageal hernias was accomplished in ten patients. Patients undergoing Toupe fundoplication had a 13 per cent dysphagia rate less than 4 weeks postoperatively and a 0% dysphagia rate greater than four weeks postoperatively. Patients undergoing Nissen fundoplication had a 16 per cent dysphagia rate less than 4 weeks postoperatively, 2 per cent dysphagia rate greater than 4 weeks postoperatively and no dysphagia at 6 weeks postoperatively. Recurrent symptomatic reflux occurred in 1.4 per cent of Nissen fundoplications and 6.7 per cent of Toupe fundoplications. Of Nissen and paraesophageal repairs 14.2 per cent had reflux and 14.3 per cent of Toupe and paraesophageal repairs had recurrent symptomatic reflux. Overall, complication rate was low. Use of mesh to repair large paraesophageal hernias resulted in a recurrence rate of 0 per cent. There was no instance of infection or bowel fistulization related to the use of mesh. We conclude that laparoscopic Nissen fundoplication in patients with normal esophageal motility is associated with a low rate of dysphagia and a low rate of recurrent reflux. Toupe fundoplication when used in reflux patients with poor esophageal motility is associated with a low rate of dysphagia and an acceptable rate of recurrent reflux. Laparoscop

摘要

腹腔镜修复术治疗胃食管反流病现已成为一种被认可的治疗方法。然而,在完全360度尼氏胃底折叠术与部分270度图普胃底折叠术之间的手术选择上仍存在争议。此外,对于食管动力差的患者,手术的恰当选择也存在一些争议。另一类食管裂孔疝患者是食管旁疝患者。关于这些患者的治疗方法的问题包括在修复时是否采用抗反流手术以及补片在这些大疝修补中的作用。本回顾性研究旨在比较腹腔镜尼氏胃底折叠术和图普胃底折叠术在食管动力正常和异常患者中的治疗结果。此外,对食管旁疝患者亚组进行研究,以确定这些患者的最佳手术方法。在本研究中,对1995年至2001年期间连续的188例患者进行了回顾性分析。纳入了在此期间所有出现食管裂孔疝手术问题的患者。所有有食管反流的患者均接受了内镜检查。除急诊嵌顿患者外,所有患者均进行了食管测压。对那些认为有必要确立诊断的患者进行了pH探头检测。对于食管旁疝患者,尽可能使用上消化道造影来明确解剖结构。所有有食管反流的患者首先接受药物治疗试验。食管动力正常的食管反流患者接受360度尼氏胃底折叠术。那些食管动力差(小于65毫米汞柱)的患者接受腹腔镜270度图普胃底折叠术。出现食管旁疝的患者接受腹腔镜修复术。如果可能,对这些患者术前进行食管测压,若记录到正常蠕动则行尼氏胃底折叠术。如果术前记录到食管动力差,则行图普胃底折叠术。必要时使用补片加强膈食管裂孔以完成无张力修复。患者由其初级胃肠病学家和外科医生进行随访。术后必要时进行包括内镜检查、pH探头检测和上消化道造影在内的随访研究,以记录出现的任何问题。在该研究的188例患者中,141例患者接受了尼氏胃底折叠术,21例患者接受了尼氏胃底折叠术并修复食管旁疝,15例接受了图普胃底折叠术,7例接受了图普胃底折叠术并修复食管旁疝,4例仅接受食管旁疝修复术。183例患者接受了腹腔镜手术。188例患者中有5例最初接受了开放手术,其中2例是因为其食管旁疝的大小。这3例患者中有3例对多年前在其他机构进行的远期手术进行了再次手术。该研究纳入了22例食管动力差的患者(11.7%)。15例患者需要图普胃底折叠术,而7例患者需要图普胃底折叠术并修复食管旁疝。10例患者完成了食管旁疝的补片修复。接受图普胃底折叠术的患者术后不到4周吞咽困难发生率为13%,术后超过4周吞咽困难发生率为0%。接受尼氏胃底折叠术的患者术后不到4周吞咽困难发生率为16%,术后超过4周吞咽困难发生率为2%,术后6周无吞咽困难。尼氏胃底折叠术患者中1.4%出现复发性症状性反流,图普胃底折叠术患者中6.7%出现复发性症状性反流。在尼氏胃底折叠术与食管旁疝修复术患者中,14.2%出现反流,在图普胃底折叠术与食管旁疝修复术患者中,14.3%出现复发性症状性反流。总体而言,并发症发生率较低。使用补片修复大的食管旁疝导致复发率为0%。没有与补片使用相关的感染或肠瘘病例。我们得出结论,食管动力正常的患者行腹腔镜尼氏胃底折叠术吞咽困难发生率低且复发性反流率低。用于食管动力差的反流患者的图普胃底折叠术吞咽困难发生率低且复发性反流率可接受。腹腔镜……

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