Nonactin biosynthesis: disruption of the polyketide synthase genes, nonKJ, in Streptomyces griseus leads to an overall 96 decrease in macrotetrolide production, yet a net increase in nonactin analogues which incorporate isobutyrate.
作者信息
Walczak R J, Nelson M E, Priestley N D
机构信息
Department of Chemistry The University of Montana, Missoula, Montana 59812-1656, USA.
出版信息
J Am Chem Soc. 2001 Oct 24;123(42):10415-6. doi: 10.1021/ja005749o.