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青春期前和青春期后进行嗅球切除术后未成熟雄性大鼠的性功能障碍

Sexual impairment of inexperienced male rats following pre- and postpuberal olfactory bulbectomy.

作者信息

Larsson K

出版信息

Physiol Behav. 1975 Feb;14(2):195-9. doi: 10.1016/0031-9384(75)90165-1.

DOI:10.1016/0031-9384(75)90165-1
PMID:1161824
Abstract

Olfactory bulbectomy of sexually inexperienced male rats prevented the occurrence of sexual behavior in most of the operated animals. This effect was observed in rats bulbectomized before puberty as well as after puberty. Bulbectomized rats which had heterosexual experience prior to the operation did not deviate from intact rats. Males living in cohabition with intact males prior to the operation showed only minor deficits in their mating performances. It was concluded that the olfactory lobe while of only minor importance for maintenance of mating once sexual behavior has been initiated, plays an important role in initiation of sexual behavior of the male rat. Furthermore, since treatment with testosterone of prepuberally bulbectomized rats did not stimulate the animals to sexual activity it was concluded that the sexual impairment following bulbectomy of isolated males presumably is not due to an impaired production of gonadal secretions.

摘要

对性经验不足的雄性大鼠进行嗅球切除后,大多数接受手术的动物都无法出现性行为。这种效应在青春期前和青春期后接受嗅球切除的大鼠中均有观察到。术前有异性接触经验的嗅球切除大鼠与未做手术的大鼠没有差异。术前与未做手术的雄性大鼠同居的雄性大鼠在交配表现上仅有轻微缺陷。得出的结论是,嗅叶虽然在性行为启动后对维持交配的重要性较小,但在雄性大鼠性行为的启动中起着重要作用。此外,由于对青春期前接受嗅球切除的大鼠用睾酮治疗并不能刺激其进行性活动,因此得出结论,单独饲养的雄性大鼠嗅球切除后的性障碍可能并非由于性腺分泌受损所致。

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Sexual impairment of inexperienced male rats following pre- and postpuberal olfactory bulbectomy.青春期前和青春期后进行嗅球切除术后未成熟雄性大鼠的性功能障碍
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