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颈椎结核性脊柱炎合并系统性红斑狼疮。

Cervical tuberculous spondylitis associated with systemic lupus erythematosus.

作者信息

Berker M, Atalay B, Söylemezoğlu F, Arioğul S, Palaoğlu S

机构信息

Department of Neurosurgery, Hacettepe University School of Medicine, Sihhiye, Ankara, 06100, Turkey.

出版信息

Spinal Cord. 2001 Oct;39(10):549-53. doi: 10.1038/sj.sc.3101203.

Abstract

STUDY DESIGN

A case report of cervical tuberculous spondylitis associated with systemic lupus erythematosus (SLE). Infection is a frequent problem in SLE, especially in patients hospitalised with the complications of the disease. Tuberculous spondylitis very rarely occurs in SLE patients, and cervical involvement has not been previously reported.

CASE REPORT

A 54-year-old female patient was admitted to our hospital with a complaint of neck pain radiating to her shoulder of 2 months' duration. The neurological examination was completely normal and radiological investigations revealed narrowing, angulation and destruction of the end plates of the 5th and 6th cervical vertebrae. She has received corticosteroid and colchicine treatment for the diagnosis of SLE during the last 10 years. The anterior cervical approach was used and pyogenic material was debrided from the C5-6 intervertebral space, and an otogenous bone graft with a Smith Robinson type fusion was performed.

CONCLUSION

High doses of corticosteroids are implicated as a risk factor for infection in SLE patients. Early diagnosis and appropriate medical and surgical treatment, as well as increased awareness of higher susceptibility to opportunistic infections, such as tuberculous spondylitis, are keystones for decreasing morbidity and mortality in patients with SLE.

摘要

研究设计

一例颈椎结核性脊柱炎合并系统性红斑狼疮(SLE)的病例报告。感染是SLE患者常见的问题,尤其是在因该病并发症住院的患者中。结核性脊柱炎在SLE患者中极为罕见,且此前尚未有颈椎受累的报道。

病例报告

一名54岁女性患者因颈部疼痛放射至肩部2个月入院。神经系统检查完全正常,影像学检查显示第5、6颈椎椎体终板狭窄、成角和破坏。在过去10年中,她因SLE诊断接受了皮质类固醇和秋水仙碱治疗。采用颈前路入路,从C5-6椎间隙清除脓性物质,并进行了Smith Robinson型融合的耳源性骨移植。

结论

高剂量皮质类固醇被认为是SLE患者感染的危险因素。早期诊断、适当的药物和手术治疗,以及提高对机会性感染(如结核性脊柱炎)更高易感性的认识,是降低SLE患者发病率和死亡率的关键。

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Cervical tuberculous spondylitis associated with systemic lupus erythematosus.
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