人类免疫缺陷病毒患者CD4 + T淋巴细胞计数低时多部位皮内暴露后狂犬病疫苗接种失败
Failure of multiple-site intradermal postexposure rabies vaccination in patients with human immunodeficiency virus with low CD4+ T lymphocyte counts.
作者信息
Tantawichien T, Jaijaroensup W, Khawplod P, Sitprija V
机构信息
Queen Saovabha Memorial Institute, Thai Red Cross Society, and Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
出版信息
Clin Infect Dis. 2001 Nov 15;33(10):E122-4. doi: 10.1086/324087. Epub 2001 Oct 12.
Human immunodeficiency virus (HIV)-infected patients with low CD4(+) T lymphocyte counts had a poor neutralizing antibody response to pre- and postexposure rabies vaccination. This study of HIV-infected patients with CD4(+) T lymphocyte counts < 200/microL indicated that patients had a poor response after 4-site intradermal vaccinations (4-4-4-0-2-2, doubling the intradermal doses of cell-culture rabies vaccine).
人类免疫缺陷病毒（HIV）感染且CD4(+) T淋巴细胞计数低的患者，对暴露前和暴露后狂犬病疫苗接种的中和抗体反应较差。这项针对CD4(+) T淋巴细胞计数<200/微升的HIV感染患者的研究表明，患者在进行4部位皮内接种（4-4-4-0-2-2，即细胞培养狂犬病疫苗皮内剂量加倍）后反应较差。
Zotero 插件