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[儿童大脑和小脑室管膜瘤]

[Cerebral and cerebellar ependymomas in children].

作者信息

Wislawski J, Bondarzewska-Nawrocka B

出版信息

Neurol Neurochir Pol. 1975 Jul-Aug;9(4):519-25.

PMID:1167243
Abstract

Clinical analysis of 63 cerebral and cerebellar ependymomas in children aged up to 14 years showed that in the initial period of the disease the diagnosis based only on clinical manifestations may be difficult, before the appearance of signs of raised intracranial pressure eintraventricular or paraventricular ependymomas may cause attacks of vomiting, abdominal pains or signs of meningeal irritation. In every case with supposed brain tumour the child should be referred to a specialist since the results are better in earlier diagnosed and treated cases. Histological examination of biopsy material showed presence of 5 types of ependymonas: 1. with numerous cells (63%), 2 mixed (15%), 3 malignant (11%), 4 subependymal (4%), 5, epithelial (3%). In cases with subtotal removal of the tumour the mean survival is 12 months. After radical operation of the tumour the longest survival was 16 years.

摘要

对63例14岁及以下儿童脑和小脑室管膜瘤的临床分析表明,在疾病初期,仅根据临床表现进行诊断可能较为困难,在出现颅内压升高体征之前,脑室内或脑室旁室管膜瘤可能会引起呕吐发作、腹痛或脑膜刺激征。对于每一例疑似脑肿瘤的患儿,都应转诊给专科医生,因为早期诊断和治疗的病例效果更好。活检材料的组织学检查显示存在5种类型的室管膜瘤:1. 细胞丰富型(63%),2. 混合型(15%),3. 恶性型(11%),4. 室管膜下型(4%),5. 上皮型(3%)。肿瘤次全切除病例的平均生存期为12个月。肿瘤根治性手术后最长生存期为16年。

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