Welch R M, Van Campen R
J Nutr. 1975 Feb;105(2):253-6. doi: 10.1093/jn/105.2.253.
Experiments were carried out to determine the effects of endogenous phytic acid in soybean seeds (Glycine max, var. "Amsoy") on the bioavailability of 59Fe to iron-depleted rats. Soybean plants were grown in nutrient solutions labeled with 59Fe supplied at either 0.4 or 1.0 ppm iron in solution. Immature and mature soybean seeds were harvested and fed to male rats as a single dose. The phytic acid content of the immature and mature seeds averaged 0.61 and 1.71% dry weight, respectively. Varying the nutrient solution iron concentration in the mature soybean seeds. When the 59Fe-labeled seeds were fed to iron-deficient rats, 59Fe from the mature seeds was more available than that from immature seeds even though the mature seeds contained approximately three times as much phytic acid. Autoclaving the mature seeds did not affect the absorption of 59Fe by rats from the seeds. Immature soybean seeds contained much more insoluble 59Fe than did mature soybean seeds. It was concluded that the directly correlated to the phytate content of the seeds; also immature soybean seeds apparently contain a factor or factors (other than phytic acid) that depresses iron availability.
开展了实验以确定大豆种子（大豆品种“阿姆索伊”）中内源性植酸对缺铁大鼠吸收59Fe生物利用率的影响。大豆植株种植在分别添加0.4 ppm或1.0 ppm铁的59Fe标记营养液中。收获未成熟和成熟的大豆种子，并将其作为单剂量喂给雄性大鼠。未成熟和成熟种子的植酸含量分别平均为干重的0.61%和1.71%。成熟大豆种子中营养液铁浓度不同。当将59Fe标记的种子喂给缺铁大鼠时，即使成熟种子中的植酸含量约为未成熟种子的三倍，但成熟种子中的59Fe比未成熟种子中的59Fe更易被吸收。对成熟种子进行高压灭菌处理不会影响大鼠对种子中59Fe的吸收。未成熟大豆种子中含有的不溶性59Fe比成熟大豆种子多得多。得出的结论是，这与种子中的植酸盐含量直接相关；此外，未成熟大豆种子显然含有一种或多种降低铁利用率的因素（除植酸外）。
