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绝经后骨密度低的女性维生素D缺乏症

[Hypovitaminosis D in postmenopausal women with low bone mineral density].

作者信息

Rodríguez Portales J A

机构信息

Departamento de Endocrinología, Escuela de Medicina, Pontificia Universidad Católica de Chile.

出版信息

Rev Med Chil. 2001 Aug;129(8):849-52.

Abstract

BACKGROUND

Low vitamin D levels are a risk factor for osteoporosis. In the Northern hemisphere, a high frequency of low vitamin D levels has been detected. The correction of this deficit is associated with a lower fracture risk.

AIM

To measure serum vitamin D levels in postmenopausal women with low bone mineral density.

MATERIAL AND METHODS

25-hydroxyvitamin D levels were measured in 40 postmenopausal women aged 50 to 74 years old, with a spine bone mineral density of less than 2 standard deviation of the values for young individuals. Serum calcium, phosphorus and calcium dietary intake were also measured.

RESULTS

Mean serum 25-hydroxyvitamin D levels were 32.2 +/- 12.5 ng/ml. No correlation between vitamin D levels and other measured variables was observed. Using a cutoff value of 15 ng/ml, two women had low 25-hydroxyvitamin D levels.

CONCLUSION

In this sample of postmenopausal women, vitamin D deficiency was infrequent.

摘要

背景

维生素D水平低是骨质疏松症的一个风险因素。在北半球,已检测到维生素D水平低的高频率情况。纠正这种缺乏与较低的骨折风险相关。

目的

测量骨矿物质密度低的绝经后女性的血清维生素D水平。

材料与方法

测量了40名年龄在50至74岁之间、脊柱骨矿物质密度低于年轻人标准值2个标准差的绝经后女性的25-羟基维生素D水平。还测量了血清钙、磷和钙的膳食摄入量。

结果

血清25-羟基维生素D的平均水平为32.2±12.5 ng/ml。未观察到维生素D水平与其他测量变量之间的相关性。使用15 ng/ml的临界值,两名女性的25-羟基维生素D水平较低。

结论

在这个绝经后女性样本中,维生素D缺乏并不常见。

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