Vinas F C, Rengachary S
Department of Neurosurgery, Halifax Medical Center, 311 N Clyde Morris Blvd., Suite 310, Daytona Beach, FL, USA.
J Clin Neurosci. 2001 Nov;8(6):505-13. doi: 10.1054/jocn.2000.0950.
Sarcoidosis is a multisystemic disorder characterised by the presence of multiple noncaseating granulomas. Clinically recognisable nervous system involvement occurs in 5-16% of patients with sarcoidosis. However, the incidence of subclinical neurosarcoidosis may be higher. The following article presents a review of the disease, including its pathophysiology, clinical and radiological characteristics and treatment. Neurosarcoidosis should be included in the differential diagnosis of infectious and noninfectious neurological syndromes.
结节病是一种多系统疾病,其特征为存在多个非干酪样肉芽肿。临床上可识别的神经系统受累见于5% - 16%的结节病患者。然而,亚临床神经结节病的发病率可能更高。以下文章对该疾病进行综述,包括其病理生理学、临床和放射学特征以及治疗。神经结节病应纳入感染性和非感染性神经综合征的鉴别诊断中。