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预防老年人跌倒的干预措施。

Interventions for preventing falls in elderly people.

作者信息

Gillespie L D, Gillespie W J, Robertson M C, Lamb S E, Cumming R G, Rowe B H

机构信息

Dept of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago Medical School, PO BOX 913, Dunedin, New Zealand, 9015.

出版信息

Cochrane Database Syst Rev. 2001(3):CD000340. doi: 10.1002/14651858.CD000340.

Abstract

BACKGROUND

Approximately 30 per cent of people over 65 years of age and living in the community fall each year; the number is higher in institutions. Although less than one fall in 10 results in a fracture, a fifth of fall incidents require medical attention.

OBJECTIVES

To assess the effects of interventions designed to reduce the incidence of falls in elderly people (living in the community, or in institutional or hospital care).

SEARCH STRATEGY

We searched the Cochrane Musculoskeletal Group specialised register (January 2001), Cochrane Controlled Trials Register (The Cochrane Library, Issue 1, 2001), MEDLINE (1966 to February 2001), EMBASE (1988 to 2001 Week 14), CINAHL (1982 to March 2001), The National Research Register, Issue 1, 2001, Current Controlled Trials (www.controlled-trials.com accessed 25 May 2001), and reference lists of articles. We also contacted researchers in the field.

SELECTION CRITERIA

Randomised trials of interventions designed to minimise the effect of, or exposure to, risk factors for falling in elderly people. Main outcomes of interest were the number of fallers, or falls. Trials reporting only intermediate outcomes were excluded.

DATA COLLECTION AND ANALYSIS

Two reviewers independently assessed trial quality and extracted data. Data were pooled using the fixed effect model where appropriate.

MAIN RESULTS

Interventions likely to be beneficial: bulletA programme of muscle strengthening and balance retraining, individually prescribed at home by a trained health professional (3 trials, 566 participants, pooled relative risk (RR) 0.80, 95% confidence interval (95%CI) 0.66 to 0.98). bulletA 15 week Tai Chi group exercise intervention (1 trial, 200 participants, risk ratio 0.51, 95%CI 0.36 to 0.73). bulletHome hazard assessment and modification that is professionally prescribed for older people with a history of falling (1 trial, 530 participants, RR 0.64, 95% CI 0.49 to 0.84). A reduction in falls was seen both inside and outside the home. bulletWithdrawal of psychotropic medication (1 trial, 93 participants, relative hazard 0.34, 95%CI 0.16 to 0.74). bulletMultidisciplinary, multifactorial, health/environmental risk factor screening/intervention programmes, both for unselected community dwelling older people (data pooled from 3 trials, 1973 participants, pooled RR 0.73, 95%CI 0.63 to 0.86), and for older people with a history of falling, or selected because of known risk factors (data pooled from 2 trials, 713 participants, pooled RR 0.79, 95%CI 0.67 to 0.94). Interventions of unknown effectiveness: bulletGroup-delivered exercise interventions (9 trials, 2177 participants). bulletNutritional supplementation (1 trial, 50 participants). bulletVitamin D supplementation, with or without calcium (3 trials, 679 participants). bulletHome hazard modification in association with advice on optimising medication (1 trial, 658 participants), or in association with an education package on exercise and reducing fall risk (1 trial, 3182 participants). bulletPharmacological therapy (raubasine-dihydroergocristine, 1 trial, 95 participants). bulletFall prevention programmes in institutional settings. bulletInterventions using a cognitive/behavioural approach alone (2 trials, 145 participants). bulletHome hazard modification for older people without a history of falling (1 trial, 530 participants). bullet Hormone replacement therapy (1 trial, 116 participants). Interventions unlikely to be beneficial: bulletBrisk walking in women with an upper limb fracture in the previous two years (1 trial, 165 participants).

REVIEWER'S CONCLUSIONS: Interventions to prevent falls that are likely to be effective are now available; less is known about their effectiveness in preventing fall-related injuries. Costs per fall prevented have been established for four of the interventions and careful economic modelling in the context of the local healthcare system is important. Some potential interventions are of unknown effectiveness and further research is indicated.

摘要

背景

在社区生活的65岁以上老人中,每年约有30%的人会跌倒;在养老机构中这一比例更高。虽然每10次跌倒中导致骨折的不到1次,但五分之一的跌倒事件需要医疗处理。

目的

评估旨在降低老年人(社区生活、机构照护或医院护理)跌倒发生率的干预措施的效果。

检索策略

我们检索了Cochrane肌肉骨骼组专业注册库(2001年1月)、Cochrane对照试验注册库(《Cochrane图书馆》,2001年第1期)、MEDLINE(1966年至2001年2月)、EMBASE(1988年至2001年第14周)、CINAHL(1982年至2001年3月)、国家研究注册库(2001年第1期)、当前对照试验(www.controlled-trials.com,2001年5月25日访问)以及文章的参考文献列表。我们还联系了该领域的研究人员。

选择标准

旨在将老年人跌倒风险因素的影响或暴露降至最低的干预措施的随机试验。主要关注的结果是跌倒者数量或跌倒次数。仅报告中间结果的试验被排除。

数据收集与分析

两名评价员独立评估试验质量并提取数据。在适当情况下,使用固定效应模型汇总数据。

主要结果

可能有益的干预措施:

  • 由训练有素的健康专业人员在家中根据个人情况制定的肌肉强化和平衡再训练计划(3项试验,566名参与者,汇总相对风险(RR)0.8, 95%置信区间(95%CI)0.66至0.98)。

  • 为期15周的太极拳团体运动干预(1项试验,200名参与者,风险比0.51, 95%CI 0.36至0.73)。

  • 为有跌倒史的老年人专业制定的家庭危险因素评估与改善措施(1项试验,530名参与者,RR 0.64, 95%CI 0.49至0.84)。在家中及家外跌倒次数均减少。

  • 停用精神药物(1项试验,93名参与者,相对风险0.34, 95%CI 0.16至0.74)。

  • 针对未选择的社区居住老年人以及有跌倒史或因已知风险因素而被选择的老年人的多学科、多因素健康/环境风险因素筛查/干预计划(未选择的社区居住老年人的数据汇总自3项试验,1973名参与者,汇总RR 0.73, 95%CI 0.6至0.86;有跌倒史或因已知风险因素而被选择的老年人的数据汇总自2项试验,713名参与者, 汇总RR 0.79, 95%CI 0.67至0.94)。

效果未知的干预措施

  • 团体实施的运动干预(9项试验,2177名参与者)。

  • 营养补充(1项试验,50名参与者)。

  • 补充维生素D,无论是否同时补充钙(3项试验,679名参与者)。

  • 结合优化药物治疗建议的家庭危险因素改善措施(1项试验,658名参与者),或结合运动及降低跌倒风险教育包的家庭危险因素改善措施(1项试验,3182名参与者)。

  • 药物治疗(罗巴辛 - 双氢麦角隐亭,1项试验,95名参与者)。

  • 机构环境中的跌倒预防计划。

  • 仅采用认知/行为方法的干预措施(2项试验,145名参与者)。

  • 针对无跌倒史老年人的家庭危险因素改善措施(1项试验,530名参与者)。

  • 激素替代疗法(1项试验,116名参与者)。

不太可能有益的干预措施

  • 对前两年有上肢骨折的女性进行快走运动(1项试验,165名参与者)。

评价员结论

目前已有可能有效的预防跌倒的干预措施;但对于其预防跌倒相关损伤的效果了解较少。已确定了其中四项干预措施预防每次跌倒的成本,在当地医疗保健系统背景下进行仔细的经济建模很重要。一些潜在干预措施的效果未知,需要进一步研究。

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