一种制备核苷二磷酸的新方法。
A novel method for the preparation of nucleoside diphosphates.
作者信息
Meyers C L, Borch R F
机构信息
Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, USA.
出版信息
Org Lett. 2001 Nov 15;3(23):3765-8. doi: 10.1021/ol0167309.
PMID:11700133
Abstract
[reaction--see text] Sugar nucleoside diphosphates have been prepared using an efficient phosphate coupling reaction that employs a highly reactive zwitterionic phosphoramidate intermediate as the phosphorylating species.
摘要
[反应——见正文] 糖核苷二磷酸已通过一种高效的磷酸偶联反应制备，该反应采用高反应性的两性离子磷酰胺中间体作为磷酸化试剂。
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