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一名非亚洲患者的透明细胞丘疹病(派杰样丘疹病)。

Clear cell papulosis (pagetoid papulosis) in a non-Asian patient.

作者信息

Gianotti R, Cambiaghi S, Locatelli A, Gelmetti C

机构信息

Institute of Dermatological Sciences, IRCCS Ospedale Maggiore di Milano, University of Milan, Italy.

出版信息

Dermatology. 2001;203(3):260-1. doi: 10.1159/000051762.

Abstract

Clear cell papulosis is a recently described disorder which is characterized by multiple flat, slightly elevated, hypopigmented papules, distributed mainly on the lower part of the trunk of healthy children. Histologically, the disease shows 'clear cells' with a pagetoid appearance spread among keratinocytes in basal and suprabasal layers of the epidermis. These cells stain for AE1, CEA and EMA, making a relationship to eccrine or apocrine elements likely. All cases reported until now describe Asian children. The first European child with clear cell papulosis is presented.

摘要

透明细胞丘疹病是一种最近才被描述的疾病,其特征为多个扁平、略隆起、色素减退的丘疹,主要分布于健康儿童的躯干下部。组织学上,该病表现为具有派杰样外观的“透明细胞”散布于表皮基底层和基底上层的角质形成细胞之间。这些细胞对AE1、癌胚抗原(CEA)和上皮膜抗原(EMA)呈阳性染色,提示可能与小汗腺或大汗腺成分有关。迄今为止报道的所有病例均为亚洲儿童。本文报道了首例患透明细胞丘疹病的欧洲儿童。

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