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胃束带放置术后的生活质量:时间、体重减轻及合并症的影响

Quality of life after lap-band placement: influence of time, weight loss, and comorbidities.

作者信息

Dixon J B, Dixon M E, O'Brien P E

机构信息

Department of Surgery, Monash University, Alfred Hospital, Melbourne, Victoria, Australia.

出版信息

Obes Res. 2001 Nov;9(11):713-21. doi: 10.1038/oby.2001.96.

Abstract

OBJECTIVE

To assess the quality of life (QOL) in severely obese subjects before and after Lap-Band gastric restrictive surgery and identify factors that may influence change.

RESEARCH METHODS AND PROCEDURES

All patients, over a 3-year period, attending for preoperative assessment (n = 459) or annual review after surgery (n = 641) have completed the Short Form-36 (SF-36) health survey. Eight domain and physical component summary (PCS) and mental component summary (MCS) scores were calculated. Scores were analyzed in groups based on time after surgery and compared with community normal (CN) values. Paired preoperative and 1-year scores (n = 218) data were used to find predictors of QOL change.

RESULTS

All preoperative mean scores (n = 459) were lower than CN values, with greater impairment in the PCS (36.8 +/- 9.5 vs. CN: 51.3 +/- 8.3, p < 0.001) than in the MCS (45.7 +/- 8.2 vs. CN: 48.8 +/- 9.5, p < 0.001) scores. After 1 year, scores were closer to CN scores (PCS: 52.4 +/- 8.2 and MCS: 48.4 +/- 7.7), and these remained closer for 4 years. Preoperative obesity comorbidity, especially physical disability, was the best predictor of poor preoperative SF-36 scores and of improvement in scores at 1 year. The percentage of excess weight loss at 1 year (46 +/- 16%) was of little predictive value of improved QOL.

DISCUSSION

Severely obese subjects have poor health-related QOL as measured by the SF-36 health survey. Lap-Band surgery for this group has provided a dramatic and sustained improvement in all measures of the SF-36. Improvement is greater in those with greater preoperative disability, and the extent of weight loss is not a good predictor of improved QOL.

摘要

目的

评估重度肥胖患者在接受胃束带限制术前后的生活质量(QOL),并确定可能影响变化的因素。

研究方法与步骤

在3年期间,所有前来进行术前评估(n = 459)或术后年度复查(n = 641)的患者均完成了简短健康调查问卷(SF - 36)。计算了八个领域以及身体成分汇总(PCS)和心理成分汇总(MCS)得分。根据术后时间对得分进行分组分析,并与社区正常值(CN)进行比较。使用术前和1年时的配对得分(n = 218)数据来寻找生活质量变化的预测因素。

结果

所有术前平均得分(n = 459)均低于CN值,身体成分汇总得分(36.8±9.5 vs. CN:51.3±8.3,p < 0.001)的受损程度大于心理成分汇总得分(45.7±8.2 vs. CN:48.8±9.5,p < 0.001)。1年后,得分更接近CN得分(PCS:52.4±8.2,MCS:48.4±7.7),并且在4年内一直保持更接近的状态。术前肥胖合并症,尤其是身体残疾,是术前SF - 36得分低以及1年时得分改善的最佳预测因素。1年时多余体重减轻的百分比(46±16%)对生活质量改善的预测价值不大。

讨论

通过SF - 36健康调查测量,重度肥胖患者的健康相关生活质量较差。胃束带手术使该组患者在SF - 36的所有测量指标上都有显著且持续的改善。术前残疾程度较高的患者改善更大,体重减轻的程度并不是生活质量改善的良好预测因素。

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