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角膜交互式程序化地形图消融定制准分子激光原位角膜磨镶术治疗角膜移植术后散光。

Corneal interactive programmed topographic ablation customized photorefractive keratectomy for correction of postkeratoplasty astigmatism.

作者信息

Alessio G, Boscia F, La Tegola M G, Sborgia C

机构信息

Clinica Oculistica, Department of Otorhinolaryngology and Ophthalmology, University of Bari, Bari, Italy.

出版信息

Ophthalmology. 2001 Nov;108(11):2029-37. doi: 10.1016/s0161-6420(01)00807-7.

Abstract

OBJECTIVE

This study evaluated the efficacy, predictability, stability, and safety of a software program (Corneal Interactive Programmed Topographic Ablation [CIPTA], LIGI, Taranto, Italy), which, by transferring programmed ablation from the corneal topograph to a flying-spot excimer laser, provides customized laser ablation for correction of postkeratoplasty astigmatism.

DESIGN

Noncomparative consecutive interventional case series.

PARTICIPANTS

Ten eyes of 10 patients with a mean age of 41.4 years (range, 26-64) had CIPTA-guided photoastigmatic refractive keratectomy (PARK) at the Clinica Oculistica of Bari (Italy). Two patients were treated for hyperopic astigmatism and eight for myopic astigmatism. All the patients had irregular astigmatism after penetrating keratoplasty. OPERATION: Topography was acquired by a corneal topograph (Orbscan II, Orbtek, Inc., Salt Lake City, UT). This, together with refractive data, was processed to obtain a customized altimetric ablation profile that was transferred to a flying-spot laser (Laserscan 2000, Lasersight, Orlando, FL).

MAIN OUTCOME MEASURES

Data on uncorrected (UCVA) and best-corrected (BCVA) visual acuity, predictability, stability of refraction, and any complications were analyzed.

RESULTS

Mean follow-up was 8.4 months (range, 6-12; SD 2.4). At the last postoperative examination, seven eyes (70%) had a UCVA superior to 20/40. Three eyes (30%) had a UCVA of 20/20. Five eyes (50%) were within 0.50 diopters (D) of attempted correction in the spherical equivalent, and eight eyes (80%) within 1 D. Index of success of astigmatic correction was 0.19. All the eyes (100%) gained Snellen lines of BCVA. We did not observe any decentration and/or haze after PARK treatment performed in this study.

CONCLUSIONS

The combination of topographic data with computer-controlled flying-spot excimer laser ablation is a suitable solution for correcting irregular astigmatism after penetrating keratoplasty.

摘要

目的

本研究评估了一种软件程序(角膜交互式程序化地形消融术[CIPTA],LIGI,意大利塔兰托)的疗效、可预测性、稳定性和安全性。该程序通过将程序化消融从角膜地形图传输至飞点准分子激光,为角膜移植术后散光的矫正提供定制的激光消融。

设计

非对照连续性干预病例系列。

参与者

在意大利巴里眼科诊所,10例平均年龄41.4岁(范围26 - 64岁)患者的10只眼接受了CIPTA引导的光性散光屈光性角膜切除术(PARK)。2例患者为远视散光,8例为近视散光。所有患者在穿透性角膜移植术后均有不规则散光。

手术

通过角膜地形图仪(Orbscan II,Orbtek公司,美国犹他州盐湖城)获取地形图。将其与屈光数据一起处理,以获得定制的高度测量消融轮廓,并传输至飞点激光(Laserscan 2000,Lasersight,美国佛罗里达州奥兰多)。

主要观察指标

分析未矫正视力(UCVA)、最佳矫正视力(BCVA)、可预测性、屈光稳定性及任何并发症的数据。

结果

平均随访8.4个月(范围6 - 12个月;标准差2.4)。在最后一次术后检查时,7只眼(70%)的UCVA优于20/40。3只眼(30%)的UCVA为20/20。5只眼(50%)的等效球镜度在预期矫正值的0.50屈光度(D)以内,8只眼(80%)在1 D以内。散光矫正成功率为0.19。所有眼(100%)的BCVA均提高了Snellen视力行数。在本研究中进行的PARK治疗后,我们未观察到任何偏中心和/或 haze。

结论

地形数据与计算机控制的飞点准分子激光消融相结合是矫正穿透性角膜移植术后不规则散光的合适解决方案。

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