[The prevalence of renal artery stenosis in patients with coronary artery disease].

OBJECTIVE

To understand the prevalence of renal artery stenosis(RAS) in patients with coronary artery disease(CAD) and the relations among coronary artery disease, renal artery stenosis, hypertension and renal insufficiency.

METHODS

280 patients with coronary artery disease or suspected coronary disease were carried out renal artery angiography after coronary angiography over 1 year period.

RESULTS

Of the total patient cohort, 43(15.3%) had significant RAS (> or = 50%), 3(1.0%) were obstructed and 14 (5.0%) were bilateral. 36 (19.1%) were diagnosed as having significant RAS among 188 CAD patients. 7 patients with significant RAS were found among 92 patients without significant coronary artery stenosis, all of them were found in the group of 22 patients with mild coronary artery atheroscloresis. The prevalence of significant RAS was 19.6% and 7.9% as referred to with or without hypertension, P < 0.05. 10 patients (55.6%) had significant RAS in 18 patients with mild renal insufficiency as compared to 33 patients (12.6%) had significant RAS in 262 patients with normal renal function, P < 0.05. In the subgroup of CAD, the prevalence of significant RAS were 15.3%, 17.1%, 25.4% in single vessel disease, two vessel disease and triple vessel disease patients, P < 0.05. 35 patients (81.4%) had hypertension among these 43 patients with RAS with 24 (56.0%) patient's blood pressure difficult to control.

CONCLUSIONS

RAS is a frequent finding in patients with CAD, especially in triple vessel disease patients. Hypertension is closely related to RAS, it should be the risk factor of RAS, and can be the clinical manifestation of RAS. CAD patients with renal insufficiency but without history of chronic glomerulonephritis may indicate RAS.