Beidel D C, Ferrell C, Alfano C A, Yeganeh R
Maryland Center for Anxiety Disorders, Department of Psychology, University of Maryland, College Park, Maryland, USA.
Psychiatr Clin North Am. 2001 Dec;24(4):831-46. doi: 10.1016/s0193-953x(05)70266-5.
The concept of shyness in young children is not new; however, only recently has it been recognized that childhood SAD is a prevalent and severe disorder, with both immediate and long-term implications for academic, social, and emotional functioning. With the recognition that this disorder can result in severe lifetime impairment, both pharmacologic and psychosocial interventions for youth with social phobia are now beginning to be developed, and their efficacy, to be determined. The study of efficacious pharmacologic treatments with childhood anxiety disorders is limited at this time. There has been even less research regarding pharmacotherapy samples of children with childhood social phobia or social anxiety only. Only seven clinical trials have been conducted, and among those, only three were placebo-controlled, double-blind studies. In all of the open-labeled trials, anxious children showed improvement on both SSRIs and benzodiazepines; however, two of the three double-blind studies were unable to replicate these treatment benefits compared with placebo. The inability to find treatment effects may be a manifestation of the small sample sizes used and the comorbidity of the samples used to date. Further examination of the SSRIs and benzodiazepines with placebo-controlled studies is needed to provide more conclusive support for the efficacy of pharmacologic treatment. Similar to pharmacologic studies, research has begun to accumulate that sheds light on effective psychosocial interventions for childhood social phobia. Future research investigating the relative contribution of specific treatment components will allow for greater efficiency in the delivery of these services. Currently, which components are necessary or sufficient is unknown, although, based on meta-analyses conducted with adult outcome studies, exposure in some form seems to be the key ingredient. In addition, little attention has been given to developmental considerations regarding understanding the utility of specific psychosocial treatment components. For example, Spence et al reported that younger socially phobic children (aged 7-9 years) experienced difficulty in understanding the concept of "cognitive challenging," thus necessitating a reduction of this treatment component for this group. In addition, because differences in treatment effects across age groups was not reported, is it unclear whether the addition of a cognitive challenging component is even warranted. Similarly, Beidel et al reported significant improvement rates without the inclusion of a specific cognitive restructuring component. Thus, future research is needed to clarify the exact utility of including this intervention in treatment. Investigations have begun to accumulate that focus solely on the treatment of childhood social phobia, as opposed to general anxiety symptoms. As a result, preliminary evidence supports the use of pharmacologic and psychosocial treatments. Nonetheless, further research is needed to provide a better understanding of the efficacy of different interventions and, in the case of psychosocial treatments, different treatment components for socially phobic children across different developmental periods. Moreover, controlled treatment outcome studies that include specific measures of social anxiety and functioning, in addition to DSM diagnostic criteria, should provide a better (i.e., more thorough) evaluation of specific treatment effects for socially phobic children and adolescents.
幼儿害羞的概念并不新鲜;然而,直到最近人们才认识到儿童社交焦虑障碍是一种普遍且严重的疾病,对学业、社交和情感功能有着直接和长期的影响。随着人们认识到这种疾病会导致严重的终身损害,针对社交恐惧症青少年的药物和心理社会干预措施目前已开始研发,其疗效有待确定。目前,关于儿童焦虑症有效药物治疗的研究有限。关于仅患有儿童社交恐惧症或社交焦虑症儿童的药物治疗样本的研究更少。仅进行了七项临床试验,其中只有三项是安慰剂对照的双盲研究。在所有开放标签试验中,焦虑儿童在使用选择性5-羟色胺再摄取抑制剂(SSRI)和苯二氮卓类药物后均有改善;然而,三项双盲研究中有两项未能与安慰剂相比重复这些治疗效果。未能发现治疗效果可能是所用样本量小以及迄今所用样本存在共病的表现。需要通过安慰剂对照研究进一步检验SSRI和苯二氮卓类药物,以更确凿地支持药物治疗的疗效。与药物研究类似,关于儿童社交恐惧症有效心理社会干预措施的研究也开始积累。未来研究特定治疗成分的相对贡献将提高这些服务的提供效率。目前,哪些成分是必要的或充分的尚不清楚,不过,根据对成人结果研究进行的荟萃分析,某种形式的暴露似乎是关键因素。此外,在理解特定心理社会治疗成分的效用方面,很少有人关注发育方面的考虑。例如,斯彭斯等人报告说,年龄较小的社交恐惧症儿童(7至9岁)在理解“认知挑战”概念方面有困难,因此需要减少该组的这一治疗成分。此外,由于未报告各年龄组治疗效果的差异,尚不清楚是否甚至有必要增加认知挑战成分。同样,贝德尔等人报告说,在不包括特定认知重构成分的情况下,改善率也很高。因此,需要未来的研究来阐明在治疗中纳入这种干预的确切效用。已经开始积累一些仅关注儿童社交恐惧症治疗而非一般焦虑症状的研究。因此,初步证据支持使用药物和心理社会治疗。尽管如此,仍需要进一步研究,以更好地理解不同干预措施的疗效,以及就心理社会治疗而言,不同发育阶段社交恐惧症儿童的不同治疗成分的疗效。此外,除了《精神疾病诊断与统计手册》(DSM)诊断标准外,纳入社交焦虑和功能特定测量的对照治疗结果研究,应该能更好地(即更全面地)评估社交恐惧症儿童和青少年的特定治疗效果。