转移性腺癌穿破布鲁赫膜，酷似脉络膜黑色素瘤。
Metastatic adenocarcinoma with rupture through the Bruch membrane simulating a choroidal melanoma.
作者信息
Read R W, Green R L, Rao N A
机构信息
Department of Ophthalmology, University of Alabama School of Medicine, 700 18th Street S, EFH 601, Birmingham, AL 35233, USA.
出版信息
Am J Ophthalmol. 2001 Dec;132(6):943-5. doi: 10.1016/s0002-9394(01)01147-3.
PURPOSE
To report a case of adenocarcinoma metastatic to the choroid with rupture through the Bruch membrane, thus, simulating a choroidal melanoma.
METHODS
Interventional case report. Evaluation in a university-based clinic, including a complete eye examination, fluorescein angiography, and ultrasonography; oncological evaluation; and eventual enucleation with histopathological study, including immunohistochemical stains.
RESULTS
A 62-year-old Hispanic female presented with visual loss, right eye, of short duration because of a choroidal mass with retinal detachment. Ultrasonography showed a dome-shaped lesion with an eccentric collar-button projection and medium internal reflectivity, which suggested a choroidal melanoma. Initial systemic evaluation was negative. Severe pain necessitated enucleation, RE, and histopathology of the choroidal mass demonstrated an adenocarcinoma. Further examination revealed a left, upper lobe, nonsmall cell lung carcinoma.
CONCLUSION
Metastatic choroidal tumors may present, although rarely, with collar-button configurations.
目的
报告一例腺癌转移至脉络膜并穿破布鲁赫膜，从而酷似脉络膜黑色素瘤的病例。
方法
介入性病例报告。在大学附属医院门诊进行评估，包括全面的眼部检查、荧光素血管造影和超声检查；肿瘤学评估；最终进行眼球摘除及组织病理学研究，包括免疫组织化学染色。
结果
一名62岁的西班牙裔女性因脉络膜肿物伴视网膜脱离导致右眼短期内视力丧失。超声检查显示一个穹顶形病变，有偏心的领扣样凸起且内部回声中等，提示脉络膜黑色素瘤。最初的全身评估为阴性。剧烈疼痛促使进行右眼眼球摘除，脉络膜肿物的组织病理学检查显示为腺癌。进一步检查发现左肺上叶非小细胞肺癌。
结论
转移性脉络膜肿瘤虽罕见，但可能呈现领扣样形态。
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