通过磁共振成像追踪神经垂体生殖细胞瘤的最早阶段：病例报告
Neurohypophyseal germinoma traced from its earliest stage via magnetic resonance imaging: case report.
作者信息
Oishi M, Morii K, Okazaki H, Tamura T, Tanaka R
机构信息
Department of Neurosurgery, Brain Research Institute, Niigata University, 1-757 Asahimachi-doori, Niigata city, Niigata, 951-8585, Japan.
出版信息
Surg Neurol. 2001 Oct;56(4):236-41. doi: 10.1016/s0090-3019(01)00575-4.
BACKGROUND
We report a case in which magnetic resonance imaging (MRI) documented the formation of a neurohypophyseal germinoma from its earliest stage.
CASE DESCRIPTION
A 9-year-old girl presented with polyuria, polydipsia, and growth retardation. Urinary and endocrinological examination indicated diabetes insipidus (DI) and growth hormone deficiency. No clear evidence of a mass in the hypothalamo-pituitary area was apparent on the first MRI scan. Follow-up MRIs and endocrinological examinations revealed that a tumor, arising from the stalk and posterior lobe of the pituitary gland, formed a mass and caused anterior pituitary function to deteriorate. Histologic diagnosis was germinoma based on open biopsy.
CONCLUSION
Radiologic findings in this case indicated the primary site of this intrasellar germinoma to be the hypothalamo-neurohypophyseal region, designating this a "neurohypophyseal germinoma."
背景
我们报告了一例磁共振成像（MRI）记录了神经垂体生殖细胞瘤从最早阶段开始形成的病例。
病例描述
一名9岁女孩出现多尿、多饮和生长发育迟缓。尿液和内分泌检查提示尿崩症（DI）和生长激素缺乏。首次MRI扫描时，下丘脑-垂体区域未发现明显的肿块证据。后续的MRI检查和内分泌检查显示，起源于垂体柄和后叶的肿瘤形成了肿块，并导致垂体前叶功能恶化。经开放活检，组织学诊断为生殖细胞瘤。
结论
该病例的影像学表现表明，这种鞍内生殖细胞瘤的原发部位是下丘脑-神经垂体区域，将其命名为“神经垂体生殖细胞瘤”。
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