基因与环境在情绪和行为障碍方面的相互作用。
Gene-environment interplay in relation to emotional and behavioral disturbance.
作者信息
Rutter Michael, Silberg Judy
机构信息
Social, Genetic and Developmental Psychiatry Research Center, Institute of Psychiatry, London SE5 8AF, UK.
出版信息
Annu Rev Psychol. 2002;53:463-90. doi: 10.1146/annurev.psych.53.100901.135223.
The conceptual and methodological issues involved in the study of gene-environment correlations (rGE) and interactions (GxE) are discussed in historical context. Quantitative genetic findings are considered with respect to rGE and GxE in relation to emotional and behavioral disturbance. Key conceptual and substantive implications are outlined in relation to both genetic and environmental risk mediation, with a brief note on evolutionary considerations.
本文在历史背景下讨论了基因-环境相关性（rGE）和相互作用（GxE）研究中涉及的概念和方法问题。结合情绪和行为障碍，对rGE和GxE的数量遗传学研究结果进行了考量。概述了与基因和环境风险中介相关的关键概念和实质性影响，并简要提及了进化方面的考量。
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