Rosen M A
Department of Anesthesia and Perioperative Care, Box 0648, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0648, USA.
Yonsei Med J. 2001 Dec;42(6):669-80. doi: 10.3349/ymj.2001.42.6.669.
Many of the anesthetic considerations for fetal procedures and surgery are identical to those for nonobstetric surgery during pregnancy, including concern for maternal safety, avoidance of both teratogenic drugs and fetal asphyxia, and the prevention of preterm labor and delivery. Anesthesia is required for the mother and quite often the fetus to perform many fetal procedures. Fetal procedures and surgery can be divided into subgroups according to their anesthetic requirements. For example: procedures that only require a needle insertion into the uterus but not into the fetus, such as intrauterine infusions; laser surgical photocoagulation of the communicating placental circulation for twin-twin transfusion syndrome (TTTS) and radio-frequency umbilical cord ablation for managing twin reversed arterial perfusion (TRAP), which are not really fetal procedures, rather they are placental or cord procedures; surgical procedures performed directly on the fetus; and the EX-utero Intrapartum Treatment (EXIT) procedure. Anesthetic considerations also depend on other factors, such as the location of the placenta. Unlike maternal surgery, for fetal procedures, the fetus is not an innocent bystander for whom the least anesthetic interference is used. Instead, the fetus can be the primary patient and may benefit from anesthesia, with close monitoring of the anesthetic effects to ensure well-being. Fetal asphyxia, hypoxia, or distress can be most effectively recognized, predicted, and avoided by fetal monitoring. Monitoring is also crucial for assessing the fetal response to corrective maneuvers.
许多胎儿手术的麻醉注意事项与孕期非产科手术相同,包括关注母体安全、避免使用致畸药物和胎儿窒息,以及预防早产和分娩。母亲和胎儿常常都需要麻醉才能进行许多胎儿手术。胎儿手术可根据其麻醉要求分为不同亚组。例如:仅需将针插入子宫而非胎儿体内的手术,如宫内输液;用于双胎输血综合征(TTTS)的胎盘交通循环激光手术光凝和用于处理双胎反向动脉灌注(TRAP)的射频脐带消融,这些实际上并非胎儿手术,而是胎盘或脐带手术;直接对胎儿进行的外科手术;以及产时宫外治疗(EXIT)手术。麻醉注意事项还取决于其他因素,如胎盘位置。与母体手术不同,对于胎儿手术,胎儿并非只需最少麻醉干预的无辜旁观者。相反,胎儿可能是主要患者,可能从麻醉中获益,同时密切监测麻醉效果以确保其健康。通过胎儿监测能够最有效地识别、预测和避免胎儿窒息、缺氧或窘迫。监测对于评估胎儿对矫正操作的反应也至关重要。