Sevre K, Rostrup M
Hjerte-Lunge-Senteret, Ullevål universitetssykehus 0407 Oslo.
Tidsskr Nor Laegeforen. 2001 Oct 30;121(26):3059-64.
Heart rate variability and baroreflex sensitivity are used to assess the activity in the autonomic nervous system. Heart rate variability is a measure of the tonic autonomic heart rate control, whereas baroreflex sensitivity measures the dynamic autonomic heart rate control.
On the basis of relevant literature and our own research, this article reviews the most commonly used techniques for measuring heart rate variability and baroreflex sensitivity, as well as results from selected studies.
Reduced heart rate variability and reduced baroreflex sensitivity may be related to increased risk for malignant ventricular arrhythmias and sudden death in patients with coronary artery disease. These parameters are also distorted in patients with hypertension. Furthermore, heart rate variability has been suggested as a tool for monitoring anaesthesia depth.
Even though these methods are useful in pathophysiological studies of the autonomic nervous system, results from clinical studies have been diverging. Further investigation is required before these methods may be incorporated in clinical practice.
心率变异性和压力反射敏感性用于评估自主神经系统的活动。心率变异性是对自主性心率控制张力的一种测量,而压力反射敏感性则测量动态自主性心率控制。
基于相关文献和我们自己的研究,本文回顾了测量心率变异性和压力反射敏感性最常用的技术以及所选研究的结果。
心率变异性降低和压力反射敏感性降低可能与冠心病患者恶性室性心律失常和猝死风险增加有关。这些参数在高血压患者中也会出现异常。此外,心率变异性已被提议作为监测麻醉深度的一种工具。
尽管这些方法在自主神经系统的病理生理学研究中很有用,但临床研究结果却存在分歧。在这些方法可纳入临床实践之前,还需要进一步研究。