Salmi L, Leroy-Matheron C, LeBesnerais P, Rosanval O, Duvaldestin P, Gouault-Heilmann M
Service d'anesthésie-réanimation, CHU Henri-Mondor, 94010 Créteil, France.
Ann Fr Anesth Reanim. 2001 Nov;20(9):799-802. doi: 10.1016/s0750-7658(01)00487-7.
A type II heparin-induced thrombocytopenia (HIT) was diagnosed in a 64-year-old woman at day 20 of intravenous unfractionated heparin (UFH) therapy, given after myocardial infarction treated by angioplasty and intracoronary stent. The infarction was complicated by a mitral insufficiency that led to a mitral valve replacement. Cardiopulmonary bypass was successfully performed with sodium danaparoid (Orgaran), as an alternative to UFH, without thrombotic or haemorrhagic complications and the follow-up was uneventful.
一名64岁女性在接受静脉普通肝素(UFH)治疗第20天时被诊断为II型肝素诱导的血小板减少症(HIT),该治疗是在心肌梗死经血管成形术和冠状动脉内支架治疗后进行的。梗死并发二尖瓣关闭不全,导致二尖瓣置换。使用达那肝素钠(Orgaran)作为UFH的替代品成功进行了体外循环,未出现血栓形成或出血并发症,随访情况良好。