在地球上的前生物分子进化过程中，甲亚胺和氰与一氧化碳的反应。

The reactions of methanimine and cyanogen with carbon monoxide in prebiotic molecular evolution on earth.

作者信息

Aylward N, Bofinger N

机构信息

Centre for Instrumental and Developmental Chemistry, Queensland University of Technology, George St., Brisbane, Queensland 4000, Australia.

出版信息

Orig Life Evol Biosph. 2001 Dec;31(6):481-500. doi: 10.1023/a:1012702913934.

DOI:10.1023/a:1012702913934

PMID:11770257

Abstract

A primeval atmosphere is proposed containing simple molecules such as formaldehyde, ammonia, carbon monoxide, cyanogen and hydrogen cyanide, which have been detected in space. Chemical reactions are described for the formation of aziridine-2-one and di-azirine-3-one derivatives as potential precursors for the original synthesis of amino-acids, proteins, pyrimidines, purines, nicotinamide and flavin. The reactions have been shown to be kinetically feasible from the overall enthalpy changes in the ZKE approximation at the MP2/6-31G* level.

摘要

有人提出原始大气中含有甲醛、氨、一氧化碳、氰和氰化氢等简单分子，这些分子已在太空中被探测到。文中描述了氮杂环丁烷-2-酮和二氮杂环丙烯-3-酮衍生物形成的化学反应，这些衍生物是氨基酸、蛋白质、嘧啶、嘌呤、烟酰胺和黄素原始合成的潜在前体。从MP2/6-31G*水平的ZKE近似中的总焓变来看，这些反应在动力学上是可行的。