Impaired venous hemodynamics in a minority of patients with chronic leg ulcers due to sickle cell anemia.

作者信息

Chalchal H, Rodino W, Hussain S, Haq I, Panetta T, Solomon W, Gillette P, Braverman A S

机构信息

Division of Hematology-Oncology, Department of Medicine, Division of Vascular Surgery, Department of Surgery, Health Sciences Center at Brooklyn, State University of New York, USA.

出版信息

Vasa. 2001 Nov;30(4):277-9. doi: 10.1024/0301-1526.30.4.277.

DOI:10.1024/0301-1526.30.4.277

PMID:11771212

Abstract

BACKGROUND

Chronic or recurrent leg ulceration occurs in 25% of sickle cell anemia patients, but not in the remaining 75%. Doppler studies of venous function were normal in 16 sickle cell anemia patients with leg ulcers.

PATIENTS AND METHODS

Venous Duplex Ultrasound was used to study 33 sickle cell anemia patients with chronic leg ulcers.

RESULTS

Six of the 33 patients had venous reflux in at least one leg.

CONCLUSIONS

Venous insufficiency may contribute to the development of leg ulcers in a minority of sickle cell anemia patients. A minority of sickle cell anemia patients with chronic leg ulcers can be shown to have leg venous reflux by duplex ultrasound imaging.

摘要