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吸入性鼻用糖皮质激素的疗效、安全性及患者偏好:相关已发表数据综述

Efficacy, safety, and patient preference of inhaled nasal corticosteroids: a review of pertinent published data.

作者信息

Blaiss M S

机构信息

Department of Pediatrics and Medicine, University of Tennessee, Memphis, TN, USA.

出版信息

Allergy Asthma Proc. 2001 Nov-Dec;22(6 Suppl 1):S5-10.

Abstract

Most clinical studies of inhaled nasal corticosteroids have established comparable safety and efficacy; therefore, there remains little to distinguish the various products from each other in the treatment of allergic rhinitis. However, patient preference is recognized increasingly as an important factor in selecting appropriate treatment. This review discusses the different methodologies that have been used to measure patient preference for intranasal corticosteroids. Patient questionnaires and other instruments for assessment that are used to measure such preferences are discussed as well as several different study designs. Now, the challenge is to implement more studies that show the reliability and consistency of instruments used to assess patient preference.

摘要

大多数吸入性鼻用糖皮质激素的临床研究已证实其安全性和疗效相当;因此,在治疗变应性鼻炎方面,各种产品之间几乎没有什么区别。然而,患者偏好日益被视为选择合适治疗方法的一个重要因素。本综述讨论了用于衡量患者对鼻用糖皮质激素偏好的不同方法。还讨论了用于测量此类偏好的患者问卷和其他评估工具,以及几种不同的研究设计。现在,挑战在于开展更多研究,以证明用于评估患者偏好的工具的可靠性和一致性。

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