Ghosh A, Kelly S P, Mathews J, Cooper P N, Macdermott N
Department of Neurology, Manchester Royal Infirmary, Manchester, UK.
J Neurol Neurosurg Psychiatry. 2002 Jan;72(1):119-21. doi: 10.1136/jnnp.72.1.119.
The management of acute optic neuritis by neurologists and ophthalmologists in the north west of England was assessed in the light of the Optic Neuritis Treatment Trial (ONTT) recommendations. A questionnaire on a fictitious case of typical unilateral optic neuritis was mailed to all consultant ophthalmologists and neurologists working in the North West and Merseyside Health Authorities. They were then asked to comment on management of the case. Fifty two out of 86 ophthalmologists and 20 out of 28 neurologists replied. The overall response rate was 63%. Sixty five per cent of neurologists and 46% of ophthalmologists would investigate a typical case of acute optic neuritis further. Forty six per cent of neurologists and 36% of ophthalmologists were likely to arrange MRI of the brain or orbit. Significantly more neurologists (55%) than ophthalmologists (9%) chose to treat with intravenous methylprednisolone (p<0.005). Significantly more ophthalmologists (64%) than neurologists (32%) chose not to give steroids (p<0.025). Oral prednisolone alone was rarely selected for treatment. Respondents were more likely to discuss multiple sclerosis with the referring doctor than with the patient. Only 32% of ophthalmologists and 20% of neurologists would clearly mention the possibility of improvement to the patient. Clear differences in practice between ophthalmologists and neurologists remain. A consensus on practice guidelines on the issues raised might be useful.
根据视神经炎治疗试验(ONTT)的建议,对英格兰西北部神经科医生和眼科医生治疗急性视神经炎的情况进行了评估。一份关于典型单侧视神经炎虚构病例的调查问卷被邮寄给了在西北和默西塞德郡卫生当局工作的所有眼科顾问医生和神经科医生。然后要求他们对该病例的治疗发表意见。86名眼科医生中有52名、28名神经科医生中有20名进行了回复。总体回复率为63%。65%的神经科医生和46%的眼科医生会对典型的急性视神经炎病例进行进一步检查。46%的神经科医生和36%的眼科医生可能会安排脑部或眼眶的磁共振成像(MRI)检查。选择静脉注射甲基强的松龙治疗的神经科医生(55%)明显多于眼科医生(9%)(p<0.005)。选择不使用类固醇的眼科医生(64%)明显多于神经科医生(32%)(p<0.025)。单独使用口服强的松龙进行治疗的情况很少被选择。与转诊医生相比,受访者更倾向于与患者讨论多发性硬化症。只有32%的眼科医生和20%的神经科医生会明确向患者提及病情改善的可能性。眼科医生和神经科医生在实际操作上仍存在明显差异。就所提出的问题达成实践指南的共识可能会有所帮助。