[计算机辅助骨组织形态计量学系统的开发与应用]

[The development and application of computer-aided bone histomorphometry system].

作者信息

Tang T, Dai K, Gu D, Xue W, Liao W

机构信息

Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2001 Dec;18(4):580-2.

PMID:11791313

Abstract

The aim of this study is to develop a Computer-aided Bone Histomorphometry System. The method is based on the Micro-graphical Digital System composed of microscope, digital camera, computer and related programs. The methodology was developed to measure the basic data on each image of visual field of hard bone tissue with computer-assistance. Following this, the parameters of bone volume, bone structure and bone metabolism were calculated based on the standardization of bone histomorphometry. Such method has been used in the experimental and clinical studies of osteoporosis to predict the fracture risk and evaluate the drug effect.

摘要

本研究的目的是开发一种计算机辅助骨组织形态计量学系统。该方法基于由显微镜、数码相机、计算机和相关程序组成的显微数字系统。开发该方法是为了在计算机辅助下测量硬骨组织视野中每个图像的基本数据。在此基础上，根据骨组织形态计量学的标准化计算骨体积、骨结构和骨代谢的参数。这种方法已用于骨质疏松症的实验和临床研究，以预测骨折风险和评估药物效果。