Splieth C, Rosin M, Gellissen B
Department of Operative Dentistry, Periodontology, and Pediatric Dentistry, Ernst Moritz Arndt University, Greifswald, Germany.
Clin Oral Investig. 2001 Dec;5(4):250-3. doi: 10.1007/s00784-001-0130-7.
The aim of the study was to assess the efficacy of removing dentine caries chemomechanically with Carisolv and with round burs. In 24 extracted permanent teeth each, caries removal with Carisolv or rotating round burs was monitored by checking the hardness of the dentine with a dental explorer and stopped at 12 teeth in each group when either (a) a leather-hard texture was reached or (b) a sharp scratching sound was heard. After embedding and sectioning (400 microm), caries activity of the remaining dentine was assessed using methyl red dye. In microscope images (7x) of the samples, the mean depth of the pink (caries-active, pH<5.5) and yellow (pH>5.5) staining of each carious lesion was calculated. Using a round bur, the depth of caries-active and -inactive lesions was significantly greater when a leather-hard texture (51-58 microm) was reached than when a sharp scratching sound was reached (19-25 microm, t-test, P<0.05). For teeth treated with Carisolv, only the depth of the caries-inactive dentine differed significantly. Regardless of the clinical criterion for caries removal, Carisolv treatment resulted in higher mean depths of caries-active dentine (71-78 microm) than conventional caries removal using the round bur (19-51 microm), while the mean depths of the caries-inactive dentine differed minimally. Thus, caries removal with Carisolv leaves up to a mean of 50 microm more carious dentine than round burs.
本研究的目的是评估使用Carisolv和圆钻化学机械去除牙本质龋的疗效。在24颗拔除的恒牙中,分别使用Carisolv或旋转圆钻去除龋坏组织,通过用牙科探针检查牙本质硬度来监测龋坏组织的去除情况,当每组达到12颗牙齿时停止,停止条件为:(a)达到皮革样硬度或(b)听到尖锐的刮擦声。包埋并切片(400微米)后,使用甲基红染料评估剩余牙本质的龋活性。在样本的显微镜图像(7倍)中,计算每个龋损的粉红色(龋活性,pH<5.5)和黄色(pH>5.5)染色的平均深度。使用圆钻时,达到皮革样硬度(51 - 58微米)时龋活性和非活性病变的深度显著大于听到尖锐刮擦声时(19 - 25微米,t检验,P<0.05)。对于用Carisolv治疗的牙齿,只有非龋活性牙本质的深度有显著差异。无论去除龋坏组织的临床标准如何,与使用圆钻进行传统龋坏组织去除相比,Carisolv治疗导致龋活性牙本质的平均深度更高(71 - 78微米),而非龋活性牙本质的平均深度差异最小。因此,与圆钻相比,使用Carisolv去除龋坏组织后,平均会残留多达50微米的龋坏牙本质。