[副肿瘤性库欣综合征导致低钾血症后出现严重代谢性碱中毒]

[Severe metabolic alkalosis following hypokalemia from a paraneoplastic Cushing syndrome].

作者信息

Dubé L, Daenen S, Kouatchet A, Soltner C, Alquier P

机构信息

Département d'anesthésie-réanimation, CHU Angers, 4, rue Larrey, 49035 Angers, France.

出版信息

Ann Fr Anesth Reanim. 2001 Dec;20(10):860-4. doi: 10.1016/s0750-7658(01)00518-4.

DOI:10.1016/s0750-7658(01)00518-4

PMID:11803847

Abstract

Metabolic alkalosis is frequently observed in critically ill patients. Etiologies are numerous but endocrinal causes are rare. We report a case of a patient with severe respiratory insufficiency, metabolic alkalosis and hypokalemia. The evolution was fatal. Further explorations revealed an ectopic Adrenocorticotropine Hormone syndrome. The initial tumor was probably a small cell lung carcinoma.

摘要

代谢性碱中毒在重症患者中很常见。病因众多，但内分泌原因罕见。我们报告一例患有严重呼吸功能不全、代谢性碱中毒和低钾血症的患者。病情发展是致命的。进一步检查发现异位促肾上腺皮质激素综合征。最初的肿瘤可能是小细胞肺癌。