单剂量应用催产素对男性射精时间和精液参数的影响。
The effect of single-dose oxytocin application on time to ejaculation and seminal parameters in men.
作者信息
Walch K, Eder R, Schindler A, Feichtinger W
机构信息
Department of Obstetrics and Gynecology, Kaiser Franz Josef Hospital, Vienna, Austria.
出版信息
J Assist Reprod Genet. 2001 Dec;18(12):655-9. doi: 10.1023/a:1013115301159.
PURPOSE
To report the effect of a single dose of oxytocin on ejaculation time and seminal parameters.
METHODS
The prospective randomized clinical study was performed at a private assisted reproduction technology center and included 103 consecutive healthy men (semen donors or husbands of IVF patients). Oxytocin (16 IU) were administered intranasally to 49 subjects, randomly assigned to the study group just before masturbation to ejaculation. The time needed for ejaculation as well as the semen parameters was recorded according to the WHO standards, and compared to the control group of 54 subjects with no prior oxytocin treatment.
RESULTS
No significant difference was noted between the two groups concerning ejaculation time and semen parameters.
CONCLUSIONS
Although the administration of oxytocin stimulates sexual behavior and performance in mammalian species, our data indicate that oxytocin has no detectable effect on ejaculation time and seminal parameters after intranasal application in normal, healthy men.
目的
报告单次注射催产素对射精时间和精液参数的影响。
方法
这项前瞻性随机临床研究在一家私立辅助生殖技术中心进行，纳入了103名连续的健康男性（精液捐赠者或试管婴儿患者的丈夫）。49名受试者被随机分配到研究组，在手淫射精前经鼻给予催产素（16国际单位）。根据世界卫生组织标准记录射精所需时间以及精液参数，并与54名未接受过催产素治疗的对照组受试者进行比较。
结果
两组在射精时间和精液参数方面未发现显著差异。
结论
尽管催产素的给药可刺激哺乳动物的性行为和表现，但我们的数据表明，在正常健康男性经鼻应用催产素后，对射精时间和精液参数没有可检测到的影响。
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