长叶糙苏长叶变种中的环烯醚萜和苯乙醇苷类化合物

Iridoid and phenylethanoid glycosides from Phlomis longifolia var. longifolia.

作者信息

Ersöz T, Schühly W, Popov S, Handjieva N, Sticher O, Caliş I

机构信息

Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey.

出版信息

Nat Prod Lett. 2001;15(5):345-51. doi: 10.1080/10575630108041302.

DOI:10.1080/10575630108041302

PMID:11841119

Abstract

From the aerial parts of Phlomis longifolia var. longifolia four iridoid glucosides, shanzhiside methyl ester (1), 5-deoxypulchelloside I (2), lamalbide (3), phlomiol (4) and three phenylethanoid glycosides, verbascoside (5), forsythoside B (6), leucosceptoside A (7) along with the caffeic acid ester, chlorogenic acid (8) were isolated. The structures of the isolated compounds were established by spectroscopic (UV, IR, 1D- and 2D-NMR, FABMS) and chemical evidence. The structure elucidation of the iridoid compounds 2 and 3 are discussed in detail.

摘要

从长叶糙苏长叶变种的地上部分分离得到了四种环烯醚萜苷，即山栀苷甲酯（1）、5-脱氧普氏苷I（2）、拉马苷（3）、糙苏醇（4），三种苯乙醇苷，即毛蕊花糖苷（5）、连翘酯苷B（6）、白花蛇舌草苷A（7），以及咖啡酸酯绿原酸（8）。通过光谱法（紫外、红外、一维和二维核磁共振、快原子轰击质谱）和化学证据确定了分离得到的化合物的结构。详细讨论了环烯醚萜化合物2和3的结构解析。