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儿童开放性结石手术:在微创治疗时代是否合理?

Open stone surgery in children: is it justified in the era of minimally invasive therapies?

作者信息

Zargooshi J

机构信息

Department of Urology, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

BJU Int. 2001 Dec;88(9):928-31. doi: 10.1046/j.1464-4096.2001.01544.x.

Abstract

OBJECTIVE

To review experience with open surgery for paediatric urolithiasis during a 10-year period.

PATIENTS AND METHODS

The hospital records of patients up to 13 years old and treated between 1990 and 2000 for stones were reviewed; there were 310 patients (98 girls and 212 boys, aged 9 months to 13 years, mean 6.8 years).

RESULTS

The commonest symptoms were renal-ureteric colic (26.7%), gross haematuria (19%), urinary retention (16.7%), and abdominal and/or flank pain (13.2%). Because of poverty and the resultant inability to pay medical fees, 19 children presented very late with pyonephrosis (resembling peritonitis in nine) and obstructive renal atrophy in 23. In 18 other patients the delay was caused by the disappearance of pain. Delayed presentation was the most important factor in developing complications from the stone. The stones were in the calyces in 15 patients, the pelvis in 113, the ureter in 56, the bladder in 71, the urethra in 17 and in a combination of sites in 38. The mean (range, median) stone size was 27 (9-75, 22) mm; 80 (25.8%) were complete staghorn stones. Indications for open surgery were a complex stone burden (62%), ESWL failure (14.5%), need for nephrectomy (1.9%), anatomical abnormalities (2.2%), and unavailability of minimally invasive alternatives (19%). All of the nephrectomized patients underwent unilateral stone removal and contralateral nephrectomy. For parents, the cost and reliability of the result were more important than other considerations, e.g. having a large or small incision. The overall stone-free rate at discharge was 95.4% (100% for single stones). In five cases (1.6%) a repeat open procedure was needed. The mean (range, median) hospital stay was 4 (1-13, 3) days.

CONCLUSIONS

Arguments against open surgery for urolithiasis in adults should not be extrapolated to children, in whom open surgery is safe and effective. In Iran and many 'developing' countries, open surgery is less expensive, more effective, more dependable, and more easily available than minimally invasive alternatives. At least in such countries it deserves to be among the first-line therapies for paediatric urolithiasis, and urologists in less-developed countries should not decline to offer open surgery because it is almost obsolete in developed countries. Delayed presentation (through poverty and/or unawareness) contributes significantly to the morbidity of urolithiasis.

摘要

目的

回顾10年间小儿尿路结石开放手术的经验。

患者与方法

回顾了1990年至2000年间收治的13岁及以下结石患儿的医院记录;共有310例患者(98例女孩和212例男孩,年龄9个月至13岁,平均6.8岁)。

结果

最常见的症状为肾输尿管绞痛(26.7%)、肉眼血尿(19%)、尿潴留(16.7%)以及腹部和/或侧腹痛(13.2%)。由于贫困及无力支付医疗费用,19例患儿就诊时已出现严重肾积脓(其中9例类似腹膜炎),23例出现梗阻性肾萎缩。另有18例患者因疼痛消失而延误就诊。就诊延迟是结石引发并发症的最重要因素。结石位于肾盏15例,肾盂113例,输尿管56例,膀胱71例,尿道17例,多部位组合38例。结石平均(范围,中位数)大小为27(9 - 75,22)mm;80例(25.8%)为完全鹿角形结石。开放手术的指征为结石负荷复杂(62%)、体外冲击波碎石(ESWL)失败(14.5%)、需要肾切除(1.9%)、解剖异常(2.2%)以及无法采用微创替代方案(19%)。所有接受肾切除的患者均进行了单侧结石清除及对侧肾切除。对于家长而言,治疗费用及结果的可靠性比其他因素(如切口大小)更为重要。出院时总体结石清除率为95.4%(单发结石为100%)。5例(1.6%)需要再次进行开放手术。平均(范围,中位数)住院时间为4(1 - 13,3)天。

结论

针对成人尿路结石开放手术的反对观点不应套用到儿童身上,儿童开放手术安全有效。在伊朗及许多“发展中”国家,开放手术比微创替代方案成本更低、更有效、更可靠且更容易实施。至少在这些国家,开放手术应成为小儿尿路结石的一线治疗方法之一,欠发达国家的泌尿外科医生不应因开放手术在发达国家已几近淘汰而拒绝提供该治疗方式。就诊延迟(因贫困和/或缺乏认知)是尿路结石发病的重要因素。

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