VanderJagt T J, Ghattas R, VanderJagt D J, Crossey M, Glew R H
Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque 87131-5221, USA.
Life Sci. 2002 Jan 18;70(9):1035-40. doi: 10.1016/s0024-3205(01)01481-3.
Teas made from medicinal plants are commonly used by a majority of the inhabitants of New Mexico and Mexico to treat various ailments including infections, arthritis, heart disorders, headaches, fever, asthma and menstrual pain. However, little is known about the identity or chemical nature of the bioactive substances and compounds responsible for the therapeutic effects of the teas made from the leaves, seeds, flowers stems, and roots of these medicinal plants. Some of the beneficial effects of these teas may be attributable to antioxidants contained in the medicinal plants from which they are brewed. In the present study we collected 30 medicinal plants that are widely used in the Rio Grande Valley and, using a two-stage Trolox based assay, analyzed the total antioxidant capacity of aqueous extracts prepared from these plants. The antioxidant content of the aqueous extracts was substantial, ranging from 27 to 972 micromol Trolox equivalent per gram dry weight. An extract of the leaves of the plant Ilex paraguensis (Mate leaf) contained the highest amount of antioxidant, followed by the flowers of the Rosa sp. (Rosa de Castillo, 804 micromol/g), the bark of Chinchona sp. (Copalquin, 692 micromol/g), Rumex hymenosepalus stems (Cana Agria, 672 micromol/g) and the leaves of Marrubium vulgare (Mastranzo, 560 micromol/g). The plants that had the lowest antioxidant capacity were the seeds of Linum lewissii (Linasa, 29 micromol/g) and Yucca sp. plant root (Amole, 27 micromol/g). It will be useful to further analyze those plants that contain the most antioxidant activity in order to identify the active principles.
新墨西哥州和墨西哥的大多数居民常用药用植物制成的茶来治疗各种疾病,包括感染、关节炎、心脏疾病、头痛、发烧、哮喘和痛经。然而,对于这些药用植物的叶、种子、花茎和根制成的茶所具有治疗作用的生物活性物质和化合物的特性或化学性质,人们却知之甚少。这些茶的一些有益效果可能归因于用于泡茶的药用植物中所含的抗氧化剂。在本研究中,我们收集了30种在里奥格兰德河谷广泛使用的药用植物,并使用基于Trolox的两阶段分析法,分析了从这些植物制备的水提取物的总抗氧化能力。水提取物中的抗氧化剂含量相当可观,每克干重的范围为27至972微摩尔Trolox当量。巴拉圭冬青(马黛茶树叶)的叶提取物所含抗氧化剂最多,其次是蔷薇属植物的花(卡斯蒂略蔷薇,804微摩尔/克)、金鸡纳属植物的树皮(科帕尔金,692微摩尔/克)、皱叶酸模茎(卡纳阿格里亚,672微摩尔/克)和夏至草叶(马斯兰佐,560微摩尔/克)。抗氧化能力最低的植物是刘易斯亚麻籽(利纳萨,29微摩尔/克)和丝兰属植物的根(阿莫尔,27微摩尔/克)。进一步分析那些抗氧化活性最高的植物,以确定其活性成分,将是很有意义的。