Ellong A, Mvogo C E, Bella-Hiag A L, Ngosso A
Hôpital général de Douala, BP 4856, Douala, Cameroun, France.
Sante. 2001 Oct-Dec;11(4):273-6.
The authors carried out a retrospective study in order to assess the efficacy of intrabled autologous blood injections after trabeculectomy. The indication for treatment was hypotony associated with overfiltration. Twelve eyes of 12 patients including seven men (58.3%) and five women (41.67 %) underwent from one to four (mean 1.7) subconjunctival injections. The age of the patients ranged from 31 to 66 years (mean 52.4 years). All the patients were diagnosed with open-angle glaucoma. Three eyes underwent trabeculectomy with mitomycine C, one with 5-fluorouracil and eight with no antimetabolite. The mean post-needling period was 12.3 months (ranging from 7 to 28 months). After intrabled blood injections, the average intraocular pressure increased from 2.7 1.2 mmHg (ranging from 0 to 6 mmHg) to 8.2 4.2 mmHg (ranging from 4 to 16 mmHg). The difference was statistically significant (P < 0.5). After treatment, the average visual acuity increased from 1.8/10 to 3.2/10. This difference was not statistically significant (P > 0.5). However, the procedure was ineffective in two patients (16.7%) as regards intraocular pressure and in seven patients (58.3%) as regards visual acuity. Hyphema, the most frequent complication (58.3% of our cases) is usually small, transient, and without sequelae. Although it may be delayed, it may be important and it induce intraocular hypertony (10% of our cases) or it may be associated with intravital blood.
作者进行了一项回顾性研究,以评估小梁切除术后前房内自体血注射的疗效。治疗指征为与滤过过度相关的低眼压。12例患者的12只眼,包括7名男性(58.3%)和5名女性(41.67%),接受了1至4次(平均1.7次)结膜下注射。患者年龄在31至66岁之间(平均52.4岁)。所有患者均被诊断为开角型青光眼。3只眼接受了丝裂霉素C小梁切除术,1只眼接受了5-氟尿嘧啶小梁切除术,8只眼未使用抗代谢药物。针刺后的平均时间为12.3个月(范围为7至28个月)。前房内注射血液后,平均眼压从2.7±1.2 mmHg(范围为0至6 mmHg)升至8.2±4.2 mmHg(范围为4至16 mmHg)。差异具有统计学意义(P<0.5)。治疗后,平均视力从1.8/10提高到3.2/10。这种差异无统计学意义(P>0.5)。然而,该手术在2例患者(16.7%)的眼压方面以及7例患者(58.3%)的视力方面无效。前房积血是最常见的并发症(占我们病例的58.3%),通常量小、短暂且无后遗症。尽管可能会延迟出现,但可能较为严重,可导致眼内高压(占我们病例的10%),或者可能与活体血液有关。