Ye J, Ya K, Wu R
Department of Ophthalmology, Affiliated Second Hospital, Medical College of Zhejiang University, Hangzhou 310009, China.
Zhonghua Yan Ke Za Zhi. 2001 Jan;37(1):56-8.
To study the ultrastructural change of rabbit lens epithelial cells with transmission electron microscope and to observe whether low power level microwave can induce the injury of rabbit lens.
Eight rabbit eyes were exposed to 10 mW/cm(2) low power level microwave radiation for 30 hours. Transmission electron microscope was used to observe the ultrastructural changes of the lens epithelial cells. The other eye was served as self-control.
The ultrastructure of exposed lens epithelial cells changed apparently. The characteristic apoptosis cell morphological changes, such as small cell size, the decreased number of mitochondria, balloon-shaped mitochondria, etc can be seen. No obvious changes can be found in the protected self-control eyes.
The low power level microwave (10 mW/cm(2)) can induce the ultrastructural changes of rabbit lens epithelial cells, this may be the appearance of early irreversible microwave radiation injury. In regard to the pathogenic mechanism, it is necessary to perform further investigations.
用透射电子显微镜研究兔晶状体上皮细胞的超微结构变化，并观察低功率微波是否能诱导兔晶状体损伤。
八只兔眼暴露于10 mW/cm²的低功率微波辐射下30小时。用透射电子显微镜观察晶状体上皮细胞的超微结构变化。另一只眼作为自身对照。
暴露的晶状体上皮细胞超微结构明显改变。可见典型的凋亡细胞形态变化，如细胞体积变小、线粒体数量减少、线粒体呈气球状等。在作为自身对照的未受辐射眼中未发现明显变化。
低功率微波（10 mW/cm²）可诱导兔晶状体上皮细胞超微结构改变，这可能是早期不可逆微波辐射损伤的表现。关于其致病机制，有必要进行进一步研究。
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