Gu B, Wu D, Liang J
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Zhonghua Yan Ke Za Zhi. 2001 Mar;37(2):104-7.
To assess the change of cone's motion perception in primary open angle glaucoma (POAG).
Equi-luminance random dots moving test was used to determine the change of motion perception of blue, green and red cones in 51 eyes with POAG. To isolate the three kinds of cones, the blue, green and red visual targets were displayed on the yellow, purple and blue-green background respectively.
The direction discrimination thresholds of motion perception from blue, green and red cones were all damaged in POAG compared to that of the normal group, and among them the blue cone was the most obviously damaged.
These findings indicate that cone's motion perception, especially the blue cone's, may reveal pre-clinical visual nerve damage in POAG.
评估原发性开角型青光眼(POAG)中视锥细胞运动感知的变化。
采用等亮度随机点运动测试来确定51只POAG患眼的蓝、绿、红视锥细胞运动感知的变化。为分离出这三种视锥细胞,分别在黄色、紫色和蓝绿色背景上显示蓝色、绿色和红色视觉目标。
与正常组相比,POAG中蓝、绿、红视锥细胞运动感知的方向辨别阈值均受损,其中蓝视锥细胞受损最为明显。
这些发现表明,视锥细胞的运动感知,尤其是蓝视锥细胞的运动感知,可能揭示POAG临床前期的视神经损伤。