el Hajjar M, Launay S, Hossein-Foucher C, Foulard M, Robert Y
Unité de néphrologie pédiatrique, hôpital Jeanne-de-Flandre 2, avenue Oscar-Lambret 59037 Lille, France.
Arch Pediatr. 2002 Jan;9(1):21-5. doi: 10.1016/s0929-693x(01)00689-3.
Acute pyelonephritis is a common infection in children. The clinical and biological diagnosis is still sometimes difficult. For most authors, Technecium 99m dimercaptosuccinic acid scintigraphy is considered as the gold standard tool for diagnosis but it is invasive and expensive. The aim of our study was to compare the sensitivity and the specificity of B-mode sonography and power doppler to DMSA-Tc scintigraphy in acute pyelonephritis.
Forty-nine children were enrolled in this study with suspicion of pyelonephritis. All infants underwent doppler sonography and scintigraphy within 48 hours after their hospitalization. Doppler sonography criteria were increased kidney size, thickness of sinus wall, vascular defect, and various echogenicity of the kidneys (focal or diffuse hyperechogenicity or focal hypoechogenicity).
Among 28 children with a positive scintigraphy, 15 had a positive doppler sonography (sensitivity 54%) and 13 had a negative doppler sonography. Among 21 children with a negative scintigraphy, 20 had a negative doppler sonography (specificity 95%) and one had a positive doppler sonography.
In clinically suspected acute pyelonephritis, doppler sonography has a high specificity. A positive doppler sonography should avoid the use of scintigraphy.
急性肾盂肾炎是儿童常见的感染性疾病。临床及生物学诊断有时仍存在困难。对于大多数作者而言,锝99m二巯基丁二酸闪烁扫描被认为是诊断的金标准工具,但它具有侵入性且费用高昂。我们研究的目的是比较B型超声和能量多普勒相对于二巯基丁二酸-锝闪烁扫描在急性肾盂肾炎诊断中的敏感性和特异性。
本研究纳入了49名疑似肾盂肾炎的儿童。所有患儿在住院后48小时内均接受了多普勒超声检查和闪烁扫描。多普勒超声检查的标准包括肾脏增大、肾窦壁增厚、血管缺损以及肾脏回声改变(局灶性或弥漫性高回声或局灶性低回声)。
在28名闪烁扫描阳性的儿童中,15名多普勒超声检查阳性(敏感性54%),13名多普勒超声检查阴性。在21名闪烁扫描阴性的儿童中,20名多普勒超声检查阴性(特异性95%),1名多普勒超声检查阳性。
在临床疑似急性肾盂肾炎时,多普勒超声检查具有较高的特异性。多普勒超声检查阳性时应避免使用闪烁扫描。