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实验用比格犬的昼夜变化范围以及体温、血压和心率模式

Ranges of diurnal variation and the pattern of body temperature, blood pressure and heart rate in laboratory beagle dogs.

作者信息

Miyazaki Hiroyasu, Yoshida Mutsumi, Samura Keiji, Matsumoto Hiroyoshi, Ikemoto Fumihiko, Tagawa Masahiro

机构信息

Development Research Laboratories, Banyu Pharmaceutical Co., Ltd., 810 Nishijo, Menuma-machi, Osato-gun, Saitama-ken, 360-0214, Japan.

出版信息

Exp Anim. 2002 Jan;51(1):95-8. doi: 10.1538/expanim.51.95.

Abstract

Ranges in diurnal variation and the patterns of body temperature (T), blood pressure (BP), heart rate (HR) and locomotor activity (LA) in 61 laboratory beagle dogs were analyzed using a telemetry system. Body temperature, BP, HR and LA increased remarkably at feeding time. Locomotor activity increased sporadically during the other periods. Body temperature was maintained at the higher value after feeding but had decreased by 0.2 C by early the next morning. Blood pressure fell to a lower value after feeding but had increased by 2.8% by early the next morning. Heart rate decreased progressively after feeding and was 14.5% lower the next morning. This study determined that in laboratory beagles the ranges of diurnal variation and patterns of T, BP and HR are significantly different from those reported in humans and rodents, and that over 24 hr these physiological changes were associated with their sporadic wake-sleep cycles of the dogs.

摘要

使用遥测系统分析了61只实验用比格犬的体温(T)、血压(BP)、心率(HR)和运动活动(LA)的昼夜变化范围及模式。喂食时,体温、血压、心率和运动活动显著增加。在其他时间段,运动活动偶尔增加。喂食后体温维持在较高水平,但到第二天清晨下降了0.2℃。喂食后血压降至较低水平,但到第二天清晨升高了2.8%。喂食后心率逐渐下降,第二天清晨降低了14.5%。本研究确定,实验用比格犬的昼夜变化范围以及体温、血压和心率模式与人类和啮齿动物报道的显著不同,并且在24小时内,这些生理变化与犬类的零星觉醒-睡眠周期相关。

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