Mortara G, Agostini C
Pathol Eur. 1975;10(3):193-5.
The effects of cycloheximide (CHM) and chloramphenicol (CAP) on rat serum proteins and on their electrophoretic patterns have been investigated. It has been shown that total serum protein is decreased by both treatments. CHM causes a fall in transferrin and alpha2(3-8) globulin content, while CAP reduces only alpha2(3-8) globulins. Different microscopic features of hepatic steatosis are described with both drugs. The results are briefly discussed.
已研究了环己酰亚胺(CHM)和氯霉素(CAP)对大鼠血清蛋白及其电泳图谱的影响。结果表明,两种处理均使血清总蛋白降低。CHM导致转铁蛋白和α2(3 - 8)球蛋白含量下降,而CAP仅降低α2(3 - 8)球蛋白。两种药物均描述了肝脂肪变性的不同微观特征。对结果进行了简要讨论。