Kucharska-Pietura K
Katedry i Kliniki Psychiatrii AM w Lublinie.
Psychiatr Pol. 2001 Nov-Dec;35(6):979-89.
The aim of this study was the assessment of cerebral specialisation in perception of emotional chimeric drawings in 50 non-chronic schizophrenics (S), 50 chronic schizophrenics (CS), 30 right brain-damaged inpatients (P), and 50 normal controls. All were marked right handers. The assessment was performed after a four-week treatment. Structure and intensity of schizophrenia symptomatology were scored on the PANSS scale. Happy-sad chimeric face drawings (David 1989) were viewed twice in free vision. A perceiver bias towards left hemiface of chimeric drawings (LHF bias) and sad bias were scored in all subjects. Subjects rated their mood at the time of testing on a visual analogue scale. The schizophrenics and right brain-damaged inpatients showed significantly weaker LHF bias compared with healthy subjects, which may suggest right cerebral hemisphere dysfunction in perception of emotional chimeric drawings. Moreover, chronic schizophrenic patients revealed significantly weaker LHF bias and sad bias compared to non-chronic subjects. There was no correlation of left perceptual bias with clinical ratings: PANSS scale, MMSE, number of hospitalisations, neuroleptic dose, and current mood, which suggests stable properties of the perceptual deficit.
本研究旨在评估50名非慢性精神分裂症患者(S)、50名慢性精神分裂症患者(CS)、30名右脑损伤住院患者(P)和50名正常对照者对情绪嵌合图感知的大脑特异性。所有受试者均为明显的右利手。评估在为期四周的治疗后进行。采用阳性和阴性症状量表(PANSS)对精神分裂症症状的结构和强度进行评分。让受试者自由观看两次快乐-悲伤嵌合脸图(David,1989)。对所有受试者的嵌合图左半脸偏向(LHF偏向)和悲伤偏向进行评分。受试者在测试时用视觉模拟量表对自己的情绪进行评分。与健康受试者相比,精神分裂症患者和右脑损伤住院患者的LHF偏向明显较弱,这可能表明在情绪嵌合图感知方面右脑半球功能障碍。此外,与非慢性患者相比,慢性精神分裂症患者表现出明显较弱的LHF偏向和悲伤偏向。左感知偏向与临床评分(PANSS量表、简易精神状态检查表、住院次数、抗精神病药物剂量和当前情绪)之间无相关性,这表明感知缺陷具有稳定的特性。