1H磁共振波谱成像预测MRI阴性颞叶癫痫的手术结果。
1H MRSI predicts surgical outcome in MRI-negative temporal lobe epilepsy.
作者信息
Suhy J, Laxer K D, Capizzano A A, Vermathen P, Matson G B, Barbaro N M, Weiner M W
机构信息
Department of Radiology, University of California, San Francisco 94143-0138, USA.
出版信息
Neurology. 2002 Mar 12;58(5):821-3. doi: 10.1212/wnl.58.5.821.
Abstract
1H MRS imaging (MRSI) was performed on 15 patients with MRI-negative temporal lobe epilepsy (TLE) who underwent seizure surgery. The non-seizure-free patients (NSF) ipsilateral hippocampal N-acetylaspartate (NAA)/(Cr+Cho) z scores were lower than the contralateral scores (p = 0.04), and the NSF ipsilateral z scores were lower than the seizure-free patients' (SF) ipsilateral z scores (p = 0.0049). Similarly, NSF contralateral scores were lower than contralateral SF (p = 0.02). These findings suggest NAA predicts the surgical outcome in patients with TLE without evidence of mesial temporal sclerosis on MRI.
摘要
对15例接受癫痫手术的MRI阴性颞叶癫痫（TLE）患者进行了1H磁共振波谱成像（MRSI）。未无癫痫发作的患者（NSF）同侧海马N-乙酰天门冬氨酸（NAA）/（肌酸+胆碱）z评分低于对侧评分（p = 0.04），且NSF同侧z评分低于无癫痫发作患者（SF）的同侧z评分（p = 0.0049）。同样，NSF对侧评分低于对侧SF（p = 0.02）。这些发现表明，NAA可预测MRI上无内侧颞叶硬化证据的TLE患者的手术结果。
相似文献
1
1H MRSI predicts surgical outcome in MRI-negative temporal lobe epilepsy.
Neurology. 2002 Mar 12;58(5):821-3. doi: 10.1212/wnl.58.5.821.
2
Proton MR Spectroscopy in Patients with Structural MRI-Negative Temporal Lobe Epilepsy.
J Neuroimaging. 2015 Nov-Dec;25(6):1030-7. doi: 10.1111/jon.12263. Epub 2015 May 26.
3
Reduction in temporal N-acetylaspartate and creatine (or choline) ratio in temporal lobe epilepsy: does this 1H-magnetic resonance spectroscopy finding mean poor seizure control?
J Neurol Neurosurg Psychiatry. 1998 Oct;65(4):518-22. doi: 10.1136/jnnp.65.4.518.
4
5
Normalization of contralateral metabolic function following temporal lobectomy demonstrated by 1H magnetic resonance spectroscopic imaging.
Ann Neurol. 1996 Aug;40(2):236-9. doi: 10.1002/ana.410400215.
6
Time course of postoperative recovery of N-acetyl-aspartate in temporal lobe epilepsy.
Epilepsia. 2001 Feb;42(2):190-7. doi: 10.1046/j.1528-1157.2001.01300.x.
7
Morphometric MRI features are associated with surgical outcome in mesial temporal lobe epilepsy with hippocampal sclerosis.
Epilepsy Res. 2017 May;132:78-83. doi: 10.1016/j.eplepsyres.2017.02.022. Epub 2017 Mar 1.
8
A short-echo-time proton magnetic resonance spectroscopic imaging study of temporal lobe epilepsy.
Epilepsia. 2002 Sep;43(9):1021-31. doi: 10.1046/j.1528-1157.2002.50701.x.
9
Spectroscopic metabolic abnormalities in mTLE with and without MRI evidence for mesial temporal sclerosis using hippocampal short-TE MRSI.
Epilepsia. 2003 Jul;44(7):977-80. doi: 10.1046/j.1528-1157.2003.50202.x.
10
Correlation between 1H MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis.
Epilepsia. 2004 Jun;45(6):632-40. doi: 10.1111/j.0013-9580.2004.54302.x.
引用本文的文献
1
γ-Aminobutyric acid as a biomarker of the lateralizing and monitoring drug effect in patients with magnetic resonance imaging-negative temporal lobe epilepsy.
Front Neurosci. 2023 May 15;17:1184440. doi: 10.3389/fnins.2023.1184440. eCollection 2023.
2
Brain metabolic differences between temporal lobe epileptic seizures and organic non-epileptic seizures in postictal phase: a retrospective study with magnetic resonance spectroscopy.
Quant Imaging Med Surg. 2021 Aug;11(8):3781-3791. doi: 10.21037/qims-20-1147.
3
Fast, regional three-dimensional hybrid (1D-Hadamard 2D-rosette) proton MR spectroscopic imaging in the human temporal lobes.
NMR Biomed. 2021 Jun;34(6):e4507. doi: 10.1002/nbm.4507. Epub 2021 Mar 23.
4
Interictal Single-Voxel Proton Magnetic Resonance Spectroscopy of the Temporal Lobe in Dogs With Idiopathic Epilepsy.
Front Vet Sci. 2020 Sep 24;7:644. doi: 10.3389/fvets.2020.00644. eCollection 2020.
5
Correlation of Electroencephalography and Magnetic Resonance Imaging in Patients with Mesial Temporal Sclerosis.
Noro Psikiyatr Ars. 2018 May 4;55(2):135-139. doi: 10.5152/npa.2017.13783. eCollection 2018.
6
Identifying the affected hemisphere with a multimodal approach in MRI-positive or negative, unilateral or bilateral temporal lobe epilepsy.
Neuropsychiatr Dis Treat. 2014 Jan 7;10:71-81. doi: 10.2147/NDT.S56404. eCollection 2014.
7
The clinical and electrophysiological characteristics of temporal lobe epilepsy with normal MRI.
J Clin Neurol. 2006 Mar;2(1):42-50. doi: 10.3988/jcn.2006.2.1.42. Epub 2006 Mar 20.
8
Epilepsy surgery: eligibility criteria and presurgical evaluation.
Dialogues Clin Neurosci. 2008;10(1):91-103. doi: 10.31887/DCNS.2008.10.1/pryvlin.
9
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Adv Exp Med Biol. 2006;576:241-62; discussion 361-3. doi: 10.1007/0-387-30172-0_17.
10
Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study.
Neuroradiology. 2005 Dec;47(12):916-23. doi: 10.1007/s00234-005-1447-8. Epub 2005 Sep 13.
本文引用的文献
1
Magnetic resonance spectroscopy and histopathological findings in temporal lobe epilepsy.
Epilepsia. 2001 Jan;42(1):41-6. doi: 10.1046/j.1528-1157.2001.080873.x.
2
3
Predictive value of 1H MRSI for outcome in temporal lobectomy.
Neurology. 1999 Sep 11;53(4):694-8. doi: 10.1212/wnl.53.4.694.
4
Automated spectral analysis III: application to in vivo proton MR spectroscopy and spectroscopic imaging.
Magn Reson Med. 1998 Dec;40(6):822-31. doi: 10.1002/mrm.1910400607.
5
Presurgical multimodality neuroimaging in electroencephalographic lateralized temporal lobe epilepsy.
Ann Neurol. 1997 Dec;42(6):829-37. doi: 10.1002/ana.410420603.
6
Hippocampal N-acetylaspartate in neocortical epilepsy and mesial temporal lobe epilepsy.
Ann Neurol. 1997 Aug;42(2):194-9. doi: 10.1002/ana.410420210.
7
Introduction to temporal lobe epilepsy.
Epilepsy Res. 1996 Dec;26(1):141-50. doi: 10.1016/s0920-1211(96)00043-5.
8
Lateralization of temporal lobe epilepsy based on regional metabolic abnormalities in proton magnetic resonance spectroscopic images.
Ann Neurol. 1994 Feb;35(2):211-6. doi: 10.1002/ana.410350213.
9
Prognostic value of qualitative magnetic resonance imaging hippocampal abnormalities in patients undergoing temporal lobectomy for medically refractory seizures.
Epilepsia. 1994 May-Jun;35(3):520-4. doi: 10.1111/j.1528-1157.1994.tb02471.x.
10
Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro.
J Neurochem. 1992 Jul;59(1):55-61. doi: 10.1111/j.1471-4159.1992.tb08875.x.
Zotero 插件