[小脑内表皮样囊肿一例的质子磁共振波谱分析]

[Proton MRS in a case of intracerebellar epidermoid].

作者信息

Isobe Tomonori, Matsumura Akira, Anno Izumi, Yoshizawa Takashi, Itai Yuji, Nose Tadao

机构信息

Department of Neurosurgery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.

出版信息

No To Shinkei. 2002 Feb;54(2):163-6.

PMID:11889764

Abstract

We report a case of epidermoid, in which proton MR spectroscopy(MRS) provided additional information to MRI. The tumor revealed high signal intensity on T2-weighted images(WI) and low signal intensity on T1 WI. No enhancement was observed. Proton MRS was acquired with the Proton Regional Imaging of Metabolites(PRIME) method(TR/TE/measurements = 2,000 ms/136,272 ms/128 times). Proton MRS revealed lactate(Lac) peak at 1.33 ppm as negative peak at TE 136 ms and positive peak at TE 272 ms. N-acetylaspartate(NAA), creatine/phosphocreatine(Cr) and choline-containing compounds(Cho) were not visible. Lac peak without other peaks such as NAA, Cr, Cho is a unique finding of proton MRS for epidermoid and this could be useful in the differential diagnosis.

摘要

我们报告一例表皮样囊肿病例，其中质子磁共振波谱（MRS）为磁共振成像（MRI）提供了额外信息。该肿瘤在T2加权图像（WI）上显示高信号强度，在T1WI上显示低信号强度。未观察到强化。采用质子代谢物区域成像（PRIME）方法（重复时间/回波时间/测量次数=2000毫秒/136、272毫秒/128次）采集质子MRS。质子MRS显示在1.33 ppm处有乳酸（Lac）峰，在回波时间136毫秒时为负峰，在回波时间272毫秒时为正峰。N-乙酰天门冬氨酸（NAA）、肌酸/磷酸肌酸（Cr）和含胆碱化合物（Cho）均不可见。没有NAA、Cr、Cho等其他峰的Lac峰是表皮样囊肿质子MRS的独特表现，这在鉴别诊断中可能有用。