Leach C S, Rambaut P C, Di Ferrante N
Lyndon B. Johnson Space Center, National Aeronautics and Space Administration, Houston, TX 77058, USA.
Acta Astronaut. 1979 Oct;6(10):1323-33. doi: 10.1016/0094-5765(79)90124-3.
Urinary excretion of amino acids by the 9 Skylab crewmen was studied as an indicator of the metabolic effects caused by exposure to the space flight environment. Intake was consistent in quality and quantity throughout the 28, 59 and 84-day flights for each of the crewmen and complete collections were accomplished. The results indicated an increased excretion in most amino acids during the first month of flight which remained elevated in the second and third months but to a lesser extent. Additional indications of change in muscle and skeletal metabolism were observed. These results point to the desirability of obtaining additional indices of alterations in protein synthetic processes in conjunction with future space flights.
对9名天空实验室宇航员的氨基酸尿排泄情况进行了研究，以此作为暴露于太空飞行环境所引起代谢效应的一个指标。在每位宇航员28天、59天和84天的飞行过程中，摄入的食物在质量和数量上保持一致，并且完成了全部收集工作。结果表明，在飞行的第一个月，大多数氨基酸的排泄量增加，在第二个月和第三个月仍保持在较高水平，但程度有所减轻。还观察到肌肉和骨骼代谢变化的其他迹象。这些结果表明，有必要结合未来的太空飞行获取蛋白质合成过程变化的更多指标。
