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雄激素对白鼠雄性生殖道核酸合成作用的放射自显影研究(作者译)

[Radioautographic study of the action of androgens on the synthesis of nucleic acids in the male genital tract of the white mouse (author's transl)].

作者信息

Durliat M, Vendrely C

出版信息

Ann Endocrinol (Paris). 1975 May-Jun;36(3):131-43.

PMID:1190726
Abstract

A comparison was made, by autoradiographic studies, of the nucleic acids synthesis in the target organs of the male hormone, in normal mice, castrate and castrated mice with an implantation of a testosterone pellet. The results show that the response of each of these organs, to a physiological supply of hormone or to a supraphysiological supply is quite different, both in intensity and in evolution. The differences are still apparent in castrated animals. The transfer of RNA from the nucleus to the cytoplasm seems to be affected by the castration. The signification of these results is discussed.

摘要

通过放射自显影研究,对正常小鼠、去势小鼠以及植入睾酮丸粒的去势小鼠雄性激素靶器官中的核酸合成进行了比较。结果表明,这些器官中的每一个对生理水平激素供应或超生理水平激素供应的反应,在强度和演变过程上都有很大差异。在去势动物中,这些差异仍然很明显。RNA从细胞核向细胞质的转移似乎受到去势的影响。对这些结果的意义进行了讨论。

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