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[化学组成与杀菌效果之间的关系。28. 二异硫氰酸酯的制备、抗菌和驱虫作用]

[Relationships between chemical constitution and germicidial effect. 28. Preparation, antimicrobial and anthelminthic effect of diiosothiocyanates].

作者信息

Teubner H, Weuffen W, Höppe H

出版信息

Arch Exp Veterinarmed. 1975;29(4):621-9.

PMID:1190979
Abstract

In comparison with monoisothiocyanates, diisothiocyanates were either less active or of the same activity against bacteria and fungi. None of the compounds tested possessed antimicrobial activity worth investigating further. However, compound No. 2 (2,4-diisothiocyanatomethyl ethoxybenzol) and compound No. 5 (1,3-dimethyl-4,6-diisothiocyanatomethylbenzol) were more active as anthelmintics against Enchytraeus than the p-phenylene diisothiocyanates.

摘要

与单异硫氰酸酯相比,二异硫氰酸酯对细菌和真菌的活性要么较低,要么相同。所测试的化合物均不具有值得进一步研究的抗菌活性。然而,化合物2(2,4 - 二异硫氰酸酯基甲基乙氧基苯)和化合物5(1,3 - 二甲基 - 4,6 - 二异硫氰酸酯基甲基苯)作为抗蠕虫药对蚯蚓的活性比对苯二异硫氰酸酯更强。

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