Cruz-Jimenez P R, Abell M R
Cancer. 1975 Nov;36(5):1860-8. doi: 10.1002/1097-0142(197511)36:5<1860::aid-cncr2820360543>3.0.co;2-w.
Eleven cases of basal cell carcinoma of the vulvar skin are reported. There was fairly close correlation between the histologic type and the gross appearance of the lesion. The average age of the patients was 59 years, and the presenting complaint was usually that of a nodule with associated irritation or pruritus. All patients were treated surgically and none have had recurrent or metastatic disease; six patients have been followed for 12 to 25 years. The treatment of choice is wide local excision. One tumor was of particular interest in that it represented a carcinomatous change in a pre-existing premalignant fibroepithelial tumor. Basal cell carcinoma of the skin must be distinguished from adenoid cystic (basal cell) carcinoma of vestibular glands, which is a more aggressive neoplasm and which metastasizes by the lymphatic and blood vascular systems.
报告了11例外阴皮肤基底细胞癌。病变的组织学类型与大体外观之间存在相当密切的相关性。患者的平均年龄为59岁,主要症状通常是伴有刺激或瘙痒的结节。所有患者均接受了手术治疗,且均无复发或转移性疾病;6例患者已随访12至25年。首选治疗方法是广泛局部切除。有一例肿瘤特别值得关注,因为它代表了先前存在的癌前纤维上皮肿瘤发生了癌变。皮肤基底细胞癌必须与前庭大腺腺样囊性(基底细胞)癌相鉴别,后者是一种侵袭性更强的肿瘤,可通过淋巴和血管系统转移。