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[光周期光疗法与觉醒 - 睡眠节律障碍]

[Photoperiod phototherapy and wakefulness-sleep rhythm disorders].

作者信息

Poirrier R

机构信息

Centre d'Etude des Troubles de l'Eveil et du Sommeil, Service de Neurologie, CHU Sart Tilman, B-4000 Liège.

出版信息

Rev Neurol (Paris). 2001 Nov;157(11 Pt 2):S140-4.

Abstract

Bright light therapy is a recent physical treatment in chronodisabled situations. The most recognized indication is the seasonal affective disorder. However, any disease or dysfunction where a misalignment of sleep-wake and circadian rhythms may be suspected is a potential tool for this treatment. Analyses of the literature throughout the interpretation methods of the evidence based medicine indicate that bright light therapy, if not a standard, could be recommended in a number of circadian rhythm sleep disorders, mainly the delayed and advanced sleep phase syndromes. Time aspects are essential for the success of phototherapy. From this point of view, easy and practical technological means or methods, allowing to shape a Phase Response Curve in each individual to be treated, should be clear progress. A future extension of indications will also depend on the checking of essential hypotheses linking circadian and sleep-wake rhythms in diseases such as psychophysiological insomnia, multiple sclerosis, brain dysgeneses or dementias. At last, a non negligible advantage of bright light therapy appears to be its relative safety.

摘要

强光疗法是近年来用于治疗时间节律失调情况的一种物理治疗方法。最广为人知的适应症是季节性情感障碍。然而,任何怀疑存在睡眠 - 觉醒与昼夜节律失调的疾病或功能障碍都是这种治疗的潜在适用对象。通过循证医学的解释方法对文献进行分析表明,强光疗法即便不算标准治疗方法,在一些昼夜节律睡眠障碍中,主要是睡眠相位延迟综合征和睡眠相位提前综合征,也可被推荐使用。时间因素对于光疗的成功至关重要。从这一角度来看,简便实用的技术手段或方法,能够为每个待治疗个体塑造相位反应曲线,应该是一项明显的进步。适应症的未来扩展还将取决于对诸如心理生理性失眠、多发性硬化症、脑发育异常或痴呆症等疾病中昼夜节律与睡眠 - 觉醒节律之间关键假设的验证。最后,强光疗法一个不可忽视的优势似乎是其相对安全性。

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