Hernández Felipe, Pombo Marta, Dalmau Regina, Andreu Javier, Alonso Manuel, Albarrán Agustín, Velázquez María T, Tascón Juan C
Department of Cardiology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Catheter Cardiovasc Interv. 2002 Apr;55(4):491-4. doi: 10.1002/ccd.10122.
Acute coronary embolism is rarely diagnosed and it may explain why normal coronary arteries are found after or even before an acute coronary event in patients with thromboembolic risk factors. Emergency coronary angiography was performed in three patients with prior normal coronary arteries and an acute myocardial infarction, followed by primary angioplasty with low-pressure balloon inflations plus stenting and combined antiaggregation with aspirin, clopidogrel, and abciximab to disrupt the thrombi and protect distal circulation from microemboli. Angiographic success was achieved in 100%, and 6-month follow-up has been uneventful on oral anticoagulation and antiaggregation.
急性冠状动脉栓塞很少被诊断出来,这或许可以解释为何在有血栓栓塞风险因素的患者中,急性冠状动脉事件发生后甚至之前会发现冠状动脉正常。对3例既往冠状动脉正常但发生急性心肌梗死的患者进行了急诊冠状动脉造影,随后进行低压球囊扩张加支架置入的直接血管成形术,并联合使用阿司匹林、氯吡格雷和阿昔单抗进行抗聚集治疗,以破坏血栓并保护远端循环免受微栓子影响。血管造影成功率达100%,在口服抗凝和抗聚集治疗下,6个月随访期间情况平稳。