Rahaman M M, Majid M A, Monsur K A
Bull World Health Organ. 1979;57(6):977-81.
A clinical trial was carried out with 126 male patients over 2 years of age suffering from diarrhoea requiring intravenous rehydration, 80 of the patients suffering from cholera and 46 from non-cholera diarrhoea. A new "diarrhoea treatment solution" (DTS) containing sodium at a concentration of 118 mmol/litre and glucose at 44 mmol/litre was compared with the usual Dacca intravenous solution (DS) which has a sodium concentration of 133 mmol/litre and contains no glucose. The other constituents and their concentrations were the same in both solutions. All the patients responded well clinically and made an uneventful recovery. Oral water intake measured during the first 24 h was higher in the group receiving the DS. This group also excreted a significantly higher quantity of sodium in the urine. A significant fall in the level of blood glucose from the admission values occurred in both the groups; the fall was relatively less in the DTS group, this solution containing 44 mmol of glucose per litre. Further work is required to find the optimum concentration of glucose in the solution for infants and young children.
对126名2岁以上因腹泻需要静脉补液的男性患者进行了一项临床试验，其中80名患者患有霍乱，46名患有非霍乱性腹泻。将一种新的“腹泻治疗溶液”（DTS）与常用的达卡静脉溶液（DS）进行比较，DTS中钠浓度为118毫摩尔/升，葡萄糖浓度为44毫摩尔/升，而DS钠浓度为133毫摩尔/升且不含葡萄糖。两种溶液的其他成分及其浓度相同。所有患者临床反应良好，康复过程顺利。接受DS的组在前24小时内测得的口服水量更高。该组尿液中钠的排泄量也明显更高。两组患者的血糖水平均较入院时显著下降；DTS组下降相对较少，该溶液每升含有44毫摩尔葡萄糖。需要进一步开展工作以确定该溶液中适合婴幼儿的葡萄糖最佳浓度。
