Janson Annika, Alm Jan, Bremme Katarina, Skjöldebrand-Sparre Lottie, Söder Olle, Werner Sigbritt
Barnens sjukhus, Huddinge Universitetssjukhus, Stockholm.
Lakartidningen. 2002 Feb 28;99(9):899-903.
A history of thyroidal disease in a pregnant mother requires special attention. Untreated, or not adequately treated, hypothyreosis in a pregnant mother is likely to affect the neurological development of the fetus negatively. The authors refer the discussion on the need for screening for hypothyroidism in early pregnancy, but stress the need for everybody dealing with these patients (general practitioners, midwives, gynecologists, pediatricians and endocrinologists), to recognize women at risk and inform their patients on the need of careful monitoring of thyroid supplementation in case of pregnancy. On the other hand, women with Graves' disease should be carefully assessed for the presence of TRAK-antibodies, and be subject to specialist maternal care. Their babies risk neonatal thyreotoxicosis and need careful attention.
怀孕母亲有甲状腺疾病史需要特别关注。怀孕母亲未经治疗或治疗不充分的甲状腺功能减退症可能会对胎儿的神经发育产生负面影响。作者提到了关于在怀孕早期筛查甲状腺功能减退症必要性的讨论,但强调每个处理这些患者的人(全科医生、助产士、妇科医生、儿科医生和内分泌科医生)都需要识别有风险的女性,并告知患者在怀孕时需要仔细监测甲状腺补充剂的使用情况。另一方面,患有格雷夫斯病的女性应仔细评估是否存在TRAK抗体,并接受专科孕产妇护理。她们的婴儿有新生儿甲状腺毒症的风险,需要密切关注。